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23260763 | Pneumocystis jirovecii genotype associated with increased death rate of HIV-infected patients with pneumonia. | Pneumocystis jirovecii dihydropteroate synthase (DHPS) mutations have been associated with failure of sulfa prophylaxis; their effect on the outcome of patients with P. jirovecii pneumonia (PCP) remains controversial. P. jirovecii DHPS polymorphisms and genotypes were identified in 112 cases of PCP in 110 HIV-infected ... |
23260762 | [When should request a stool culture?]. | A stool culture needs a medical prescription and is justified only in a case of clearly defined acute diarrhea. The clinical context must be suggestive of a bacterial etiology. The detection of the bacterial agents has to follow a well-defined strategy to optimize a rigorous prescription. Standardized stool culture is ... |
23260759 | [Intestinal microbiota: from antibiotic-associated diarrhea to inflammatory bowel diseases]. | The intestinal microbiota is known to be composed by several hundred different bacterial species and is stable over time. Antibiotics intake induces a disturbance in the composition of intestinal microbiota which impairs its protective role against infection by pathogens. The presence of a large biomass of bacteria in ... |
23260751 | A comparison of the diagnostic performance of the ST/HR hysteresis with cardiopulmonary stress testing parameters in detecting exercise-induced myocardial ischemia. | Because ST segment depression has limited diagnostic performance at exercise electrocardiography (ECG), ST segment depression/heart rate (ST/HR) hysteresis and cardiopulmonary exercise test (CPET)-derived parameters have been proposed as alternatives to diagnose exercise-induced myocardial ischemia. We compared the dia... |
23260750 | Supplemental intravenous n-3 fatty acids and n-3 fatty acid status and outcome in critically ill elderly patients in the ICU receiving enteral nutrition. | N-3 fatty acids (FA) may have benefits in ICU patients. The aims were to identify whether FA status is altered in critical illness and to evaluate the effect of supplemental intravenous n-3 FA on plasma FA status and clinical outcome in ICU patients receiving enteral nutrition. Enterally fed patients (n = 49; 60-80 yea... |
23260749 | Low compliance with dietary recommendations for food intake among adults. | To assess the adherence to the national dietary recommendations and to identify factors contributing to dietary compliance in Switzerland. Population-based cross-sectional study in Lausanne, Switzerland (CoLaus study), 2009-2012. Dietary intake was assessed using a validated food frequency questionnaire. Participants w... |
23260748 | Education program on medical nutrition and length of stay of critically ill patients. | To evaluate the impact of a multifaceted nutritional educational intervention on the quality of nutritional therapy and clinical outcomes in critically ill patients. We conducted a prospective, non-blinded study with a non-contemporaneous control group at a 16-bed intensive care unit (ICU) at the Hospital das Clinicas,... |
23260747 | Nutritional evaluation of rapeseed protein compared to soy protein for quality, plasma amino acids, and nitrogen balance--a randomized cross-over intervention study in humans. | Plant proteins such as rapeseed have received little attention for human nutrition due to their high level of antinutritive compounds. Today, newer technologies can eliminate such compounds. The present intervention study aimed to evaluate nutritional and physiological properties of two manufactured canola proteins wit... |
23260733 | Towards a typology of rural responses to healthcare in Mexico, 1920-1960. | After the revolutionary conflicts of the 1910s, the Mexican state sought to bring peace to the country's obstreperous, rebellious and often downright unknown rural provinces through the establishment of a new social pact. Peasants were to embrace political loyalty, productivity, and secularization in return for land, e... |
23260730 | Comparison of child obesity prevention and control content in mainstream and Spanish-language US parenting magazines. | Mass media coverage of child obesity is rising, paralleling the child obesity epidemic's growth, and there is evidence that parents seek parenting advice from media sources. Yet little to no research has examined the coverage of child obesity in parenting magazines or Spanish-language media. The purpose of this study w... |
23260729 | Positive attitudes toward organic, local, and sustainable foods are associated with higher dietary quality among young adults. | Scant evidence is available on the relationship between preferences for organic, local, sustainable, and nonprocessed foods (ie, alternative food production practices) and dietary quality. This cross-sectional study examined the characteristics and dietary behaviors (eg, consumption of fruits, vegetables, fast food) of... |
23260728 | Characteristics associated with consumption of sports and energy drinks among US adults: National Health Interview Survey, 2010. | Sales of sports and energy drinks have increased dramatically, but there is limited information on regular consumers of sports and energy drinks. Characteristics associated with sports and energy drink intake were examined among a sample representing the civilian noninstitutionalized US adult population. The 2010 Natio... |
23260727 | Regular-soda intake independent of weight status is associated with asthma among US high school students. | Limited research shows an inconclusive association between soda intake and asthma, potentially attributable to certain preservatives in sodas. This cross-sectional study examined the association between regular (nondiet)-soda intake and current asthma among a nationally representative sample of high school students. An... |
23260726 | Childhood overweight/obesity and asthma: is there a link? A systematic review of recent epidemiologic evidence. | Asthma and overweight/obesity prevalence are both increasing worldwide. Overweight/obesity has been suggested as a risk factor for developing asthma. The aim of this review is to present and evaluate recent publications that help answer the question: "Is increased body weight (at least overweight status) related to ast... |
23260725 | A qualitative study of diverse experts' views about barriers and strategies to improve the diets and health of Supplemental Nutrition Assistance Program (SNAP) beneficiaries. | The Supplemental Nutrition Assistance Program (SNAP), the largest federal food assistance program, currently serves 44.7 million Americans with a budget of $75 billion in 2011. This study engaged leading experts for in-depth, semi-structured interviews to explore their opinions concerning the existing challenges and ba... |
23260724 | Written messages improve edible food waste behaviors in a university dining facility. | Sustainability and going green have become popular trends among foodservice organizations. Despite this interest, foodservice operations still produce large amounts of edible food waste and contribute significantly to waste management problems. The purpose of this operational study was to determine how to introduce foo... |
23260722 | Trends in dietary intake among US 2- to 6-year-old children, 1989-2008. | Between 1989 and 2008, obesity increased markedly in children of all ages. We examined changes in the diets of children ages 2 to 6 years in the United States between 1989 and 2008. Our study provides new insight into diet changes that might have contributed to the sharp rise in obesity during this period. Our aim was ... |
23260717 | Human gastroenteritis outbreak associated with Escherichia albertii, Japan. | Although Escherichia albertii is an emerging intestinal pathogen, it has been associated only with sporadic human infections. In this study, we determined that a human gastroenteritis outbreak at a restaurant in Japan had E. albertii as the major causative agent. |
23260716 | On statistical inference in time series analysis of the evolution of road safety. | Data collected for building a road safety observatory usually include observations made sequentially through time. Examples of such data, called time series data, include annual (or monthly) number of road traffic accidents, traffic fatalities or vehicle kilometers driven in a country, as well as the corresponding valu... |
23260712 | VEGF-C, VEGF-A and related angiogenesis factors as biomarkers of allograft vasculopathy in cardiac transplant recipients. | Cardiac allograft vasculopathy (CAV), the major cause of late allograft loss after cardiac transplantation, results from donor-directed cellular and humoral alloimmune responses. Graft vascular endothelial cells (EC) are primary targets of these destructive responses, suggesting that factors associated with endothelial... |
23260713 | Recurrent orthostatic syncope due to left atrial and left ventricular collapse after a continuous-flow left ventricular assist device implantation. | Left ventricular assist devices (LVADs) have become an established treatment for patients with advanced heart failure as a bridge to transplantation or for permanent support as an alternative to heart transplantation. Continuous-flow LVADs have been shown to improve outcomes, including survival, and reduce device failu... |
23260711 | Pre-clinical evaluation of the infant Jarvik 2000 heart in a neonate piglet model. | The infant Jarvik 2000 heart is a very small, hermetically sealed, intracorporeal, axial-flow ventricular assist device (VAD) designed for circulatory support in neonates and infants. The anatomic fit, short-term biocompatibility and hemodynamic performance of the device were evaluated in a neonate piglet model. The in... |
23260710 | Clinical outcome of mechanical circulatory support for refractory cardiogenic shock in the current era. | Mortality for refractory cardiogenic shock (RCS) remains high. However, with improving mechanical circulatory support device (MCSD) technology, the treatment options for RCS patients are expanding. We report on a recent 5-year single-center experience with MCSD for treatment of RCS. This study was a retrospective revie... |
23260709 | Utility of C4d immunostaining in the first year after pediatric and young adult heart transplantation. | C4d assessment of endomyocardial biopsies (EMBs) after heart transplantation (HTx) has been widely adopted to aid in the diagnosis of antibody-mediated rejection (AMR), yet it remains unclear whether or not to assess all patients routinely and with what frequency/duration. In this study we sought to evaluate the utilit... |
23260708 | An unexpectedly high prevalence of undiagnosed diabetes in patients awaiting lung transplantation. | Diabetes mellitus (DM) is a common complication after lung transplantation but its prevalence prior to transplantation has not been determined. We sought to determine the prevalence of and risk factors for DM in adults awaiting lung transplantation and to determine whether pre-transplant DM could be diagnosed by hemogl... |
23260707 | Clinical implications of chronic hepatitis E virus infection in heart transplant recipients. | Recent reports have shown that hepatitis E virus (HEV) infection can become chronic in solid-organ transplant recipients, but few studies have systematically investigated the clinical consequences of this chronic HEV infection in solid-organ transplant (SOT) recipients. We have undertaken an in-depth study of 6 chronic... |
23260706 | Donor-specific antibodies are associated with antibody-mediated rejection, acute cellular rejection, bronchiolitis obliterans syndrome, and cystic fibrosis after lung transplantation. | Lung transplantation is limited by chronic lung allograft dysfunction. Acute cellular rejection (ACR) is a risk factor for allograft dysfunction; however, the role of antibody-mediated rejection (AMR) is not well characterized. This was a retrospective review from 2007 to 2011 of lung transplant recipients with human l... |
23260705 | Left ventricular distensibility does not explain impaired exercise capacity in pediatric heart transplant recipients. | Despite improved ventricular function after heart transplantation, the aerobic capacity, as measured by peak oxygen consumption (VO(2 peak)) of pediatric heart transplant recipients (HTRs), remains 30% to 50% lower than age-matched healthy individuals. Research in adult HTRs suggests that diastolic dysfunction is a maj... |
23260704 | Bronchiolitis obliterans syndrome, hypogammaglobulinemia, and infectious complications of lung transplantation. | Because infection has been associated with the development of bronchiolitis obliterans syndrome (BOS), we hypothesized that post-transplant hypogammaglobulinemia would be associated with infection and BOS. Cross-sectional levels of serum immunoglobulins were measured on 2 occasions in our transplant cohort and models d... |
23260703 | Progression pattern of restrictive allograft syndrome after lung transplantation. | Restrictive allograft syndrome (RAS) is a novel form of chronic lung allograft dysfunction after lung transplantation. RAS is characterized by restrictive physiology and peripheral lung fibrosis. The purpose of the study is to analyze progression patterns of RAS. Clinical information, pulmonary function test results an... |
23260699 | Axial and centrifugal continuous-flow rotary pumps: a translation from pump mechanics to clinical practice. | The recent success of continuous-flow circulatory support devices has led to the growing acceptance of these devices as a viable therapeutic option for end-stage heart failure patients who are not responsive to current pharmacologic and electrophysiologic therapies. This article defines and clarifies the major classifi... |
23260683 | Highly sensitive detection of human cardiac myoglobin using a reverse sandwich immunoassay with a gold nanoparticle-enhanced surface plasmon resonance biosensor. | A highly sensitive reverse sandwich immunoassay for the detection of human cardiac myoglobin (cMb) in serum was designed utilizing a gold nanoparticle (AuNP)-enhanced surface plasmon resonance (SPR) biosensor. First, a monoclonal anti-cMb antibody (Mab1) was covalently immobilized on the sensor surface. AuNPs were cova... |
23260682 | Comparison of an antibody and its recombinant derivative for the detection of the small molecule explosive 2,4,6-trinitrotoluene. | Antibodies are commonly used as recognition elements in immunoassays because of their high specificity and affinity, and have seen extensive use in competitive assays for the detection of small molecules. However, these complex molecules require production either in animals or by mammalian cell cultures, and are not ea... |
23260681 | A competitive displacement assay with quantum dots as fluorescence resonance energy transfer donors. | The unique optoelectronic properties of semiconductor quantum dots (QDs) make them well-suited as fluorescent bioprobes for use in various biological applications. Modification of CdSe/ZnS QDs with biologically relevant molecules provides for multipotent probes that can be used for cellular labeling, bioassays, and loc... |
23260680 | Luminescence recognition of different organophosphorus pesticides by the luminescent Eu(III)-pyridine-2,6-dicarboxylic acid probe. | Luminescence quenching of a novel long lived Eu(III)-pyridine-2,6-dicarboxylic acid probe of 1:2 stoichiometric ratio has been studied in 0.10 volume fraction ethanol-water mixture at pH 7.5 (HEPES buffer) in the presence of the organophosphorus pesticides chlorfenvinphos (P1), malathion (P2), azinphos (P3), and paraxo... |
23260679 | Label-free electrochemical monitoring of vasopressin in aptamer-based microfluidic biosensors. | Vasopressin is an indicating biomarker for blood pressure in the human body and low vasopressin levels can be indicative of late-phase hemorrhagic shock or other traumatic injuries. In this paper we have developed an aptamer-based label-free microfluidic biosensor for the electrochemical detection of vasopressin. The d... |
23260678 | A reliable and simple method for the assay of neuroendocrine tumor markers in human urine by solid-phase microextraction-gas chromatography-triple quadrupole mass spectrometry. | Homovanillic acid (HVA), vanylmandelic acid (VMA), and 5-hydroxyindoleacetic acid (5-HIAA) are the metabolites of some catecholamines such as epinephrine, nor-epinephrine, dopamine and serotonin and their quantification is used in the diagnosis and management of patients with neurocrine tumors. A novel approach in the ... |
23260677 | An aptamer-based biosensing platform for highly sensitive detection of platelet-derived growth factor via enzyme-mediated direct electrochemistry. | In this work, a new label-free electrochemical aptamer-based sensor (aptasensor) was constructed for detection of platelet-derived growth factor (PDGF) based on the direct electrochemistry of glucose oxidase (GOD). For this proposed aptasensor, poly(diallyldimethylammonium chloride) (PDDA)-protected graphene-gold nanop... |
23260676 | Apoferritin protein nanoparticles dually labeled with aptamer and horseradish peroxidase as a sensing probe for thrombin detection. | A novel and ultrasensitive sandwich-type electrochemical aptasensor has been developed for the detection of thrombin, based on dual signal-amplification using HRP and apoferritin. Core/shell Fe(3)O(4)/Au magnetic nanoparticles (AuMNPs) loading aptamer1 (Apt1) was used as recognition elements, and apoferritin dually lab... |
23260675 | The influence of R and S configurations of a series of amphetamine derivatives on quantitative structure-activity relationship models. | Chiral molecules need special attention in drug design. In this sense, the R and S configurations of a series of thirty-four amphetamines were evaluated by quantitative structure-activity relationship (QSAR). This class of compounds has antidepressant, anti-Parkinson and anti-Alzheimer effects against the enzyme monoam... |
23260674 | Assessment of applicability domain for multivariate counter-propagation artificial neural network predictive models by minimum euclidean distance space analysis: a case study. | Alongside the validation, the concept of applicability domain (AD) is probably one of the most important aspects which determine the quality as well as reliability of the established quantitative structure-activity relationship (QSAR) models. To date, a variety of approaches for AD estimation have been devised which ca... |
23260673 | Classification of time-of-flight secondary ion mass spectrometry spectra from complex Cu-Fe sulphides by principal component analysis and artificial neural networks. | Artificial neural network (ANN) and a hybrid principal component analysis-artificial neural network (PCA-ANN) classifiers have been successfully implemented for classification of static time-of-flight secondary ion mass spectrometry (ToF-SIMS) mass spectra collected from complex Cu-Fe sulphides (chalcopyrite, bornite, ... |
23260672 | Characterisation of hydrogen bond perturbations in aqueous systems using aquaphotomics and multivariate curve resolution-alternating least squares. | Aquaphotomics is a new discipline that provides a framework for understanding changes in the structure of water caused by various perturbations, such as variations in temperature or the addition of solutes, using near infrared spectroscopy (NIRS). One of the main purposes of aquaphotomics is to identify water bands as ... |
23260668 | Poised RNA polymerase II changes over developmental time and prepares genes for future expression. | Poised RNA polymerase II (Pol II) is predominantly found at developmental control genes and is thought to allow their rapid and synchronous induction in response to extracellular signals. How the recruitment of poised RNA Pol II is regulated during development is not known. By isolating muscle tissue from Drosophila em... |
23260670 | Gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo. | Gambogic acid (GA) is a natural compound derived from Chinese herbs that has been approved by the Chinese Food and Drug Administration for clinical trials in cancer patients; however, its molecular targets have not been thoroughly studied. Here, we report that GA inhibits tumor proteasome activity, with potency compara... |
23260671 | Polyaniline coated micro-capillaries for continuous flow analysis of aqueous solutions. | The inner walls of fused silica micro-capillaries were successfully coated with polyaniline nanofibres using the "grafting" approach. The optical response of polyaniline coatings was evaluated during the subsequent redoping-dedoping processes with hydrochloric acid and ammonia solutions, respectively, that were passed ... |
23260669 | Induction of CD8+ regulatory T cells protects macaques against SIV challenge. | Efforts to develop a vaccine against HIV have so far met with limited success. Given that CD4(+) T cell activation drives the initial burst of viral replication, we explored in macaques whether an oral vaccine comprised of Lactobacillus plantarum, a commensal bacterium that favors immune tolerance, and inactivated simi... |
23260667 | MORC2 signaling integrates phosphorylation-dependent, ATPase-coupled chromatin remodeling during the DNA damage response. | Chromatin dynamics play a central role in maintaining genome integrity, but how this is achieved remains largely unknown. Here, we report that microrchidia CW-type zinc finger 2 (MORC2), an uncharacterized protein with a derived PHD finger domain and a conserved GHKL-type ATPase module, is a physiological substrate of ... |
23260666 | Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency. | Generation of induced pluripotent stem cells (iPSCs) is a process whose mechanistic underpinnings are only beginning to emerge. Here, we applied in-depth quantitative proteomics to monitor proteome changes during the course of reprogramming of fibroblasts to iPSCs. We uncover a two-step resetting of the proteome during... |
23260665 | Genetic dissection of neurotrophin signaling through the p75 neurotrophin receptor. | Structural determinants underlying signaling specificity in the tumor necrosis factor receptor superfamily (TNFRSF) are poorly characterized, and it is unclear whether different signaling outputs can be genetically dissociated. The p75 neurotrophin receptor (p75(NTR)), also known as TNFRSF16, is a key regulator of trop... |
23260664 | Telomere length correlates with life span of dog breeds. | Telomeric DNA repeats are lost as normal somatic cells replicate. When telomeres reach a critically short length, a DNA damage signal is initiated, inducing cell senescence. Some studies have indicated that telomere length correlates with mortality, suggesting that telomere length contributes to human life span; howeve... |
23260663 | Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly. | Telomeres are essential for nuclear organization in yeast and during meiosis in mice. Exploring telomere dynamics in living human cells by advanced time-lapse confocal microscopy allowed us to evaluate the spatial distribution of telomeres within the nuclear volume. We discovered an unambiguous enrichment of telomeres ... |
23260662 | Lsd1 and lsd2 control programmed replication fork pauses and imprinting in fission yeast. | In the fission yeast Schizosaccharomyces pombe, a chromosomal imprinting event controls the asymmetric pattern of mating-type switching. The orientation of DNA replication at the mating-type locus is instrumental in this process. However, the factors leading to imprinting are not fully identified and the mechanism is p... |
23260661 | Listeriosis outbreaks and associated food vehicles, United States, 1998-2008. | Listeria monocytogenes, a bacterial foodborne pathogen, can cause meningitis, bacteremia, and complications during pregnancy. This report summarizes listeriosis outbreaks reported to the Foodborne Disease Outbreak Surveillance System of the Centers for Disease Control and Prevention during 1998-2008. The study period i... |
23260660 | Uncovering a region of heat shock protein 90 important for client binding in E. coli and chaperone function in yeast. | The heat shock protein 90 (Hsp90) family of heat shock proteins is an abundantly expressed and highly conserved family of ATP-dependent molecular chaperones. Hsp90 facilitates remodeling and activation of hundreds of proteins. In this study, we developed a screen to identify Hsp90-defective mutants in E. coli. The muta... |
23260658 | RecA-promoted, RecFOR-independent progressive disassembly of replisomes stalled by helicase inactivation. | In all organisms, replication impairment is a recognized source of genomic instability, raising an increasing interest in the fate of inactivated replication forks. We used Escherichia coli strains with a temperature-inactivated replicative helicase (DnaB) and in vivo single-molecule microscopy to quantify the detailed... |
23260657 | Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway. | Damaged DNA is an obstacle during DNA replication and a cause of genome instability and cancer. To bypass this problem, eukaryotes activate DNA damage tolerance (DDT) pathways that involve ubiquitylation of the DNA polymerase clamp proliferating cell nuclear antigen (PCNA). Monoubiquitylation of PCNA mediates an error-... |
23260656 | Structural determinants of RGS-RhoGEF signaling critical to Entamoeba histolytica pathogenesis. | G protein signaling pathways, as key components of physiologic responsiveness and timing, are frequent targets for pharmacologic intervention. Here, we identify an effector for heterotrimeric G protein α subunit (EhGα1) signaling from Entamoeba histolytica, the causative agent of amoebic colitis. EhGα1 interacts with t... |
23260655 | Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. | Mixed lineage leukemia (MLL) fusion proteins cause oncogenic transformation of hematopoietic cells by constitutive recruitment of elongation factors to HOX promoters, resulting in overexpression of target genes. The structural basis of transactivation by MLL fusion partners remains undetermined. We show that the ANC1 h... |
23260654 | Crystal structure of the O(2)-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b. | We report the 3.3 Å resolution structure of dimeric membrane-bound O(2)-tolerant hydrogenase 1 from Escherichia coli in a 2:1 complex with its physiological partner, cytochrome b. From the short distance between distal [Fe(4)S(4)] clusters, we predict rapid transfer of H(2)-derived electrons between hydrogenase heterod... |
23260652 | Trends in the levels of Escherichia coli in commercially harvested bivalve shellfish from England and Wales, 1999-2008. | Temporal trends in Escherichia coli concentrations in bivalve shellfish were examined using data collected from 57 production areas around the coast of England and Wales during 1999-2008. Downward trends were detected in annual geometric means of E. coli in shellfish from 12% of the sampling points. The percentage of c... |
23260651 | Spring plankton community structure and distribution in the north and south coasts of Sfax (Tunisia) after north coast restoration. | The first phase of the Taparura Project aimed at restoring the north coast of Sfax (Tunisia), highly polluted by phosphate industry and uncontrolled phosphogypsum dumping. Before restoration of the north coast of Sfax, we investigated the state of the ecosystem in related coastal waters. To establish the impact of the ... |
23260650 | A baseline study of tropical coastal water quality in Port Dickson, Strait of Malacca, Malaysia. | Tidal variation in tropical coastal water plays an important role on physicochemical characteristics and nutrients concentration. Baseline measurements were made for nutrients concentration and physicochemical properties of coastal water, Port Dickson, Malaysia. pH, temperature, oxidation reduction potential, salinity ... |
23260649 | Reciprocal experimental transplantations to assess effects of organic enrichment on the recolonization of benthic macrofauna in a subtropical estuary. | Coastal benthic habitats are usually in a state of continuous recolonization as a consequence of natural disturbances or human activities. Recolonization patterns can be strongly affected by the quality of the sediment. We evaluated herein the macrobenthic recolonization of organically enriched sediments through a mani... |
23260648 | Broad-scale patterns of tissue-δ15N and tissue-N indices in frondose Ulva spp.; developing a national baseline indicator of nitrogen-loading for coastal New Zealand. | A survey of tissue-δ(15)N and tissue-N values in the green macroalga, Ulva, was conducted around the coast of New Zealand to determine if these indices could be used as indicators of anthropogenic nutrient loading in coastal waters. In addition, data from four case studies showed temporal and spatial responses of tissu... |
23260647 | Macrobenthos habitat potential mapping using GIS-based artificial neural network models. | This paper proposes and tests a method of producing macrobenthos habitat potential maps in Hwangdo tidal flat, Korea based on an artificial neural network. Samples of macrobenthos were collected during field work, and eight control factors were compiled as a spatial database from remotely sensed data and GIS analysis. ... |
23260646 | A baseline study of levels of mercury, arsenic, cadmium and lead in Northeast Arctic cod (Gadus morhua) from different parts of the Barents Sea. | This study is one of several baseline studies that will provide basic and reliable information about the content of undesirable substances in important species of fish caught in Norwegian waters. Concentrations of metals in the muscle and liver of more than 800 Northeast Arctic cod caught at 32 sites in the Barents Sea... |
23260630 | Variations of 210Po and 210Pb concentration in mussels (Mytilus galloprovincialis) from Didim and Izmir Bay (Turkish coast of Aegean Sea). | In this study, the activity concentrations of (210)Po and (210)Pb were determined in mussels (Mytilus galloprovincialis) collected from Didim and Izmir Bay (Turkish coast of Aegean Sea) during the period of April 2006-March 2007. The concentrations activity of (210)Po were determined spectroscopically through its 5.30 ... |
23260628 | [Single-dose intraincisional levobupivacaine infiltration in caesarean postoperative analgesia: a placebo-controlled double-blind randomized trial]. | The efficacy of single-dose intraincisional infiltration with levobupivacaine in postoperative analgesia and chronic pain after caesarean sections is unknown. A placebo-controlled double-blind randomized trial. After ethical approval, and written inform consent, 140 women scheduled for a caesarean section were randomly... |
23260626 | Repeated, long-term cycling of putative stem cells between niches in a basal chordate. | The mechanisms that sustain stem cells are fundamental to tissue maintenance. Here, we identify "cell islands" (CIs) as a niche for putative germ and somatic stem cells in Botryllus schlosseri, a colonial chordate that undergoes weekly cycles of death and regeneration. Cells within CIs express markers associated with g... |
23260627 | Seropositivity for influenza A(H1N1)pdm09 virus among frontline health care personnel. | Seroprevalence of antibodies to influenza A(H1N1)pdm09 virus among 193 emergency department health care personnel was similar among 147 non-health care personnel (odds ratio 1.4, 95% CI 0.8-2.4). Working in an acute care setting did not substantially increase risk for virus infection above risk conferred by community-b... |
23260625 | Biochemical membrane lipidomics during Drosophila development. | Lipids play critical roles in energy homeostasis, membrane structure, and signaling. Using liquid chromatography and mass spectrometry, we provide a comprehensive semiquantification of lipids during the life cycle of Drosophila melanogaster (230 glycerophospholipids, 210 sphingolipids, 6 sterols and sterol esters, and ... |
23260624 | A preceptorship programme for newly qualified nurses: a study of preceptees' perceptions. | This paper presents the evaluation of a preceptorship programme for newly-qualified nurses (NQNs) to determine preceptee engagement with the preceptorship programme, and the impact, value and sustainability of the programme from the preceptees' perspectives. The literature suggests that NQNs find the transition from st... |
23260623 | Mastering the professional role as a newly graduated registered nurse. | Professional development is a process starting during undergraduate education and continuing throughout working life. A new nurse's transition from school to work has been described as difficult. This study aims to develop a model describing the professional development of new nurses during their first years of work. T... |
23260622 | Constructing and validating a global student-centered nursing curriculum learning efficacy scale: a confirmatory factor analysis. | Previous evidence-based studies have lacked a comprehensive student-centered scale to measure the learning efficacy of pre-registered nursing students. This study developed and validated a global scale for measuring learning efficacy among pre-registered nurses in Taiwan. Evaluated nursing courses included fundamental ... |
23260620 | Promoting student learning and increasing organizational capacity to host students in residential aged care: a mixed method research study. | In Australia, the Federal government's agenda to increase clinical training places to address the forecast shortfall of nurses is driving innovation in clinical education. A student leadership model of clinical education, named the Student Nurse Led Ward model, was designed for the aged care context to provide a high n... |
23260621 | Developing global citizenship online: an authentic alternative to overseas clinical placement. | This paper presents the findings of a pilot project to develop and evaluate an international nursing module delivered using a collaborative online platform between nursing programmes in Scotland, USA and Finland. The purpose of the project was to provide an authentic international nursing experience for nursing student... |
23260619 | Preparing students for graduate study: an eLearning approach. | This paper describes the development and preliminary evaluation of an eLearning program intended to provide incoming nursing students with the basic knowledge, skills and abilities needed to succeed in graduate-level, online coursework. Using Mayer's principles (2008) for the effective design of multimedia instruction,... |
23260618 | A randomized controlled trial of the effects of brief mindfulness meditation on anxiety symptoms and systolic blood pressure in Chinese nursing students. | Previous studies suggested that mindfulness meditation effectively reduced stress-related anxiety and depression symptoms, but no research has evaluated the efficacy of mindfulness meditation in nurses and nursing students in China. To evaluate the effects of brief mindfulness meditation on the anxiety and depression s... |
23260617 | The experience of end of life care simulation at a rural Australian University. | Providing end of life care is a challenging and anxiety provoking prospect for many undergraduate nursing students and many students report a lack of preparedness in providing care. The limited availability of appropriate clinical placements limits the opportunities for nursing students to gain experience in end of lif... |
23260616 | Impact of peer teaching on nursing students: perceptions of learning environment, self-efficacy, and knowledge. | Peer teaching has been shown to enhance student learning and levels of self efficacy. The purpose of the current study was to examine the impact of peer-teaching learning experiences on nursing students in roles of tutee and tutor in a clinical lab environment. This study was conducted over a three-semester period at a... |
23260615 | The neural basis of semantic cognition: converging evidence from neuropsychology, neuroimaging and TMS. | Recent studies suggest that a complex, distributed neural network underpins semantic cognition. This article reviews our contribution to this emerging picture and traces the putative roles of each region within this network. Neuropsychological studies indicate that semantic cognition draws on at least two interacting c... |
23260614 | Associations between gross motor coordination and academic achievement in elementary school children. | We aimed to evaluate the relationship between gross motor coordination (MC) and academic achievement (AA) in a sample of Portuguese children aged 9-12 years. The study took place during the 2009/2010 school year and involved 596 urban children (281 girls) from the north of Portugal. AA was assessed using the Portuguese... |
23260613 | Thigh pain, subsidence and survival using a short cementless femoral stem with pure metaphyseal fixation at minimum 9-year follow-up. | Short femoral stems designed to spare bone stock and improve load transfer at the proximal femur level have been introduced in recent years. However, little is known on the long-term outcomes of these stems. Short cementless stems have low rate of thigh pain and subsidence as well as few revision needs at mid-term foll... |
23260612 | The process associated with motivation of a home-based Wii Fit exercise program among sedentary African American women with systemic lupus erythematosus. | To explore the process associated with the motivation for playing Wii Fit among patients with systemic lupus erythematosus (SLE). Individual in-depth semi-structured telephone interviews were conducted with 14 sedentary African American women with SLE to explore their experiences and reflect on their motivation for pla... |
23260611 | Utahns' understanding of autism spectrum disorder. | The general public has numerous misconceptions and a lack of awareness and understanding regarding some of the prevalence, characteristics, and treatments of autism. As a result, education and awareness activities to increase the general public's understanding and awareness of autism are important. This study was condu... |
23260610 | Marital formation in individuals with work-related permanent impairment. | Prior studies on the impact of disabling work injury have neglected social support as a key mediating factor. This study investigates how permanent impairment from a work injury affects marital formation, an indicator of social support and integration with the potential to affect psychosocial adjustment and the resumpt... |
23260609 | Receipt of mammography among women with intellectual disabilities: medical record data indicate substantial disparities for African American women. | Little information exists on the receipt of mammography by African American women with intellectual disabilities. Given the high rates of mortality from breast cancer among African American women and low screening rates among women with intellectual disabilities, it is important to understand the health screening behav... |
23260608 | Tourette syndrome, parenting aggravation, and the contribution of co-occurring conditions among a nationally representative sample. | Previous research suggests that parents of a child with Tourette Syndrome (TS) have lower self-concepts, higher caregiver burden, and more difficulties with home activities. However, the contributions of TS and mental, emotional, or behavioral (MEB) conditions to family functioning are difficult to identify from previo... |
23260607 | Satisfaction with healthcare services among Spanish people with disabilities. | Several studies show the relationship between patient satisfaction and quality of health services and also between disabling conditions and healthcare access, but none sufficiently analyze the factors that contribute to satisfaction among patients with disabilities. The primary aim of this paper is to quantify the impa... |
23260606 | Evaluation of an activities of daily living scale for adolescents and adults with developmental disabilities. | Activity limitations are an important and useful dimension of disability, but there are few validated measures of activity limitations for adolescents and adults with developmental disabilities. To describe the development of the Waisman Activities of Daily Living (W-ADL) Scale for adolescents and adults with developme... |
23260605 | Reduction measures and percent body fat in individuals with intellectual disabilities: a scoping review. | Individuals with intellectual disability (ID) may be more obese and extremely obese than individuals without ID. There remains an on-going debate as to the effectiveness of exercise training in decreasing body fat in different populations. This scoping review explored the effects of exercise training interventions on p... |
23260601 | Phase I clinical trial of valacyclovir and standard of care cyclophosphamide in children with endemic Burkitt lymphoma in Malawi. | Treatment options for Epstein-Barr virus (EBV)-associated Burkitt lymphoma in Africa are limited because of chemotherapy-associated toxicity. Since other EBV-associated diseases respond to antiviral agents, we investigated adding an antiviral agent, valacyclovir, to the current chemotherapy regimen in Malawi. In this p... |
23260602 | Malnutrition and poor food intake are associated with prolonged hospital stay, frequent readmissions, and greater in-hospital mortality: results from the Nutrition Care Day Survey 2010. | The Australasian Nutrition Care Day Survey (ANCDS) ascertained if malnutrition and poor food intake are independent risk factors for health-related outcomes in Australian and New Zealand hospital patients. Phase 1 recorded nutritional status (Subjective Global Assessment) and 24-h food intake (0, 25, 50, 75, 100% intak... |
23260600 | Prognostic factors associated with disease progression and overall survival in patients with myelodysplastic syndromes treated with decitabine. | Decitabine improves overall survival (OS) and reduces risk of progression to acute myeloid leukemia (AML) in myelodysplastic syndromes (MDS). In this retrospective analysis of data from 2 decitabine studies (n = 162), hemoglobin level ≥ 10 g/dL, platelet count ≥ 50 10(3)/μL, and lack of chromosome 5 or 7 abnormalities ... |
23260599 | High frequencies of response after limited primary therapy for multiple myeloma. | In an effort to maintain high primary response rates against multiple myeloma and without serious toxicity, we assessed 3 different bortezomib combinations in small numbers of patients, with combinations that included cyclophosphamide and lenalidomide in modest doses and for short courses. Remissions occurred in approx... |
23260597 | The effect of vitrification on ultrastructure of human in vitro matured germinal vesicle oocytes. | To describe the possible effects of cryotop vitrification on maturation rate and ultrastructural morphology of human in vitro matured germinal vesicle (GV) oocytes. A total of 301surplus immature GV oocytes obtained from infertile patients were allocated into two groups: (i) GV oocytes (n=150) matured in vitro (fIVM), ... |
23260596 | Altered CD16 expression on vaginal neutrophils from women with vaginitis. | Reduced CD16 expression is associated with neutrophil apoptosis. This study aimed to compare CD16 expression on neutrophils in the vagina from women with normal bacterial flora and with vaginitis. Vaginal lavages were sampled from volunteers diagnosed with bacterial vaginosis (BV, n=34), vulvovaginal candidiasis (VC, n... |
23260578 | Exploration of 1-(3-chloro-4-(4-oxo-4H-chromen-2-yl)phenyl)-3-phenylurea derivatives as selective dual inhibitors of Raf1 and JNK1 kinases for anti-tumor treatment. | Based on the roles of Raf1 and JNK1 in hepatocarcinoma development, scaffold-based drug design was employed to produce a series of compounds, which subsequently were synthesized and explored as potential dual inhibitors Raf1 and JNK1 kinases for anti-tumor treatment. The compound 1-(3-chloro-4-(6-ethyl-4-oxo-4H-chromen... |
23260576 | Enhanced bioactivity of silybin B methylation products. | Flavonolignans from milk thistle (Silybum marianum) have been investigated for their cellular modulatory properties, including cancer chemoprevention and hepatoprotection, as an extract (silymarin), as partially purified mixtures (silibinin and isosilibinin), and as pure compounds (a series of seven isomers). One chall... |
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