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6,350 | This study aims to examine the causal relationship between internet usage and BMI among the elderly, addressing a gap in existing research and providing evidence for the development of health policies targeted at the elderly population | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
25,378 | Addressing cigarette and e-cigarette use in China is key to reducing the global tobacco epidemic. Marketing exposure is one causal factor for adolescent smoking and e-cigarette use. Currently, China restricts cigarette and e-cigarette ads in public places and online; however, there may not be full policy compliance. We... | Marketing exposure | adolescent smoking | Intra | Explicit | Marketing exposure | e-cigarette use. | Intra | Explicit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
24,838 | In the realm of web-based medical crowdfunding, the importance of uploaded images cannot be overstated. Image characteristics, including the number of people depicted and the presence of youth, significantly improve fundraising results. In addition, the thematic choice of images in cancer crowdfunding efforts has a pro... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9,832 | Rare deleterious coding variants may increase risk for COPD, but multiple genes likely contribute to COPD susceptibility | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
15,696 | Ketamine is associated with structured electroencephalogram power and global coherence signatures that may enable principled anesthetic state but not dissociation monitoring | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
17,721 | LPA was positively associated with inhibitory control, and this association was stronger in bouts of LPA than in sporadic LPA. Moreover, reducing the time spent in SB or sleep and increasing the time spent in LPA, especially long-bout LPA, could be important measures for managing inhibitory control in late life. Future... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
21,094 | Higher maternal Hb may identify the risk of adverse pregnancy outcomes. Further research is required to investigate if this association is causal and to identify the underlying mechanisms | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1,766 | In both countries, the collected data fit the model well with all the hypothesized paths among the constructs being supported. Furthermore, the moderating effects of psychic distance were observed in most of the paths | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
12,646 | This study highlights the fact that salivary hypofunction definition and measurements are different across the studies. Therefore, future research efforts should focus on establishing a gold standard to define and identify salivary hypofunction throughout life and on performing longitudinal studies controlling for conf... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5,730 | Our study showed causal relationships between hypertension and changes in specific brain cortical, providing new evidence for the heart-brain axis theory | hypertension | changes in specific brain cortical | Intra | Explicit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
474 | Swallowing impairment is a clinically relevant acute and long-term complication in patients with a wide variety of cancers. More prospective studies on the course of dysphagia and impact on quality of life from baseline to long-term follow-up after various treatment modalities, including targeted therapies, are needed | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
20,432 | Our MR study revealed that the serum total bilirubin was causally associated with the risk of cholelithiasis, and the genetic predisposition to cholelithiasis was causally associated with the increased serum total bilirubin levels | serum total bilirubin | risk of cholelithiasis | Intra | Explicit | genetic predisposition to cholelithiasis | increased serum total bilirubin levels | Intra | Explicit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
12,100 | Many public health interventions cannot be evaluated using randomised controlled trials so they rely on the assessment of observational data. Techniques for evaluating public health interventions using observational data include interrupted time series analysis, panel data regression-based approaches, regression discon... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
14,190 | Our analysis clarifies how important factors contribute to mortality in ICU patients. Burst suppression appears to contribute to mortality but is primarily an effect of critical illness rather than iatrogenic use of propofol | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
205 | We investigated the effects of human resistin on atherosclerotic progression and clarified its underlying mechanisms | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
19,298 | Our findings provided new evidence that genetically predicted an extra daily cup of tea intake may causally associated with a decreased risk of bronchiectasis, pneumonia, and influenza and pneumonia | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
16,510 | We have recently developed monitoring from the injury site in patients with acute, severe traumatic spinal cord injuries to facilitate their management in the intensive care unit. This is analogous to monitoring from the brain in patients with traumatic brain injuries. This study aims to determine whether, after trauma... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
7,388 | Two cohorts were compared retrospectively using a pre-post design | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1,243 | Well premeditated intensive monitoring approach in pharmacovigilance amplifies the ADR detection, which can persuade healthcare providers into more drug safety | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10,210 | Genu and body are altered in non-suicide attempters with BD, while splenium is specifically altered in suicide attempters, independently from their psychiatric status. History of suicide attempts may be a source of heterogeneity in the association between CC alterations and BD and may partially explain the variable res... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1,450 | The effects of cotyledon damage on seedling growth and survival are relatively well established, but little is known about the effects on aspects of plant fitness such as seed number and size. Here the direct and indirect mechanisms linking cotyledon damage and plant fitness in the annual species Medicago lupulina are ... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
6,528 | Data from a genome-wide association study were analysed. MR analysis was performed using the inverse-variance weighted, MR-Egger, and weighted-median methods, accompanied by heterogeneity testing, sensitivity analysis, and pleiotropy analysis. Metabolic-pathway enrichment analysis was conducted on the preliminarily scr... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3,283 | In recent years, the association between depression and various chronic diseases has attracted widespread attention. However, the effect of depression on lung cancer incidence has not been well studied. This study aimed to explore whether depression increases the incidence of lung cancer and to analyze the mediating an... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
7,744 | Greater loneliness is associated with lower cognitive function. Although preliminary evidence is promising, additional studies are necessary to determine the causality and biological mechanisms underlying the relationship between loneliness and cognitive function. Findings should be verified in culturally diverse popul... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
7,751 | To investigate the association between medication adherence and HRQoL, thereby illustrating methodological challenges that need to be addressed | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
27,774 | Uric acid levels significantly increased during the intensive phase. Pulmonary TB patients with hyperuricemia are a risk factor for arthralgia | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
16,729 | Results supported the UTAUT model to explain participants' acceptance and use of telepsychology. They showed a causal chain in which perceived telepsychology advantages and barriers were related to telepsychology use through the perceived usefulness of and intention to use telepsychology | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
12,751 | By adopting causal transportability to consider how context may affect the success of an implementation strategy, researchers can formally diagnose when the results of a study are likely to generalize to a given setting. Moreover, selection diagrams can highlight what additional measurements would be needed in a target... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
15,280 | Genetically predicted physical activity was not robustly associated with risk of neurodegenerative disorders. Triangulating evidence across other studies is necessary in order to elucidate whether enhancing physical activity is an effective approach in preventing the onset of AD, PD, or ALS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11,956 | We conducted a genome-wide association study of AW symptom count in uniformly assessed subjects with histories of serious AW, followed by additional genotyping in independent AW subjects | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
20,074 | There are still various elements of BGDs with insufficient, ambiguous, or altogether absent evidence, and further high-quality research is required. However, there appears to be sufficient scientific justification already to recommend that practitioners treating BGDs check serum VitD levels and supplement as appropriat... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
19,690 | Both alcohol-exposed groups reported higher levels of current depressive symptoms and a higher prevalence of diagnoses of depression, anxiety, bipolar disorder, and/or attention deficit/hyperactivity disorder. No differences were noted for psychotic disorders. PAE was also associated with greater environmental stressor... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
22,851 | Cheese intake was inversely associated with gestational hypertension and gestational diabetes in MR analysis, suggesting that cheese consumption may be beneficial in preventing hypertension and diabetes during pregnancy | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
18,891 | Self-employed workers in Korea have a higher risk of self-reported mental health problems and sleep disturbances than paid workers. Further studies with a longitudinal design and structured evaluation are required to investigate the causal relationship between health problems and self-employment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
8,184 | We find an obesity paradox among persons with dysglycemia. In this population, the inverse association between obesity and smoking is much stronger than in the source population, and the extent of illness and weight loss is greater. The obesity paradox is absent among never-smokers. Among smokers, the paradox is elimin... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
26,482 | We conducted analysis to further examine the identified associations and assess potential causal relationships | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
23,768 | BMI and dietary habits were associated with the cognitive function of young children in Bangladesh. Although the cross-sectional design of the study precludes causal relationships from being determined, the study finding deserves further examination via longitudinal research | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9,052 | Research has shown that perceived unfairness contributes to higher rates of sickness absence. While shorter, but more frequent periods of sickness absence might be a possibility for the individual to get relief from high strain, long-term sickness absence might be a sign of more serious health problems. The Uncertainty... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
27,854 | The relationship between dysregulation of the immune system and reproductive health, particularly in the context of abortion, is an area of critical research. Identifying the immunological factors that contribute to abortion could provide valuable insights into its prevention and management | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5,852 | The altered z-DC in the right precentral gyrus and the anomaly causal effects from the precentral motor cortex to the ipsilateral striatum represented by the caudate nucleus might play vital roles in the pathogenesis of PD-pRBD. It was speculated that the attenuation of FC from the precentral motor cortex to the subcor... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
25,789 | Coronary heart disease and Ischemic stroke may increase the risk of hydrocephalus | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11,345 | Many of the included studies approached risk factors in similar ways and found factors that were associated with back pain but were not obvious risk factors as causality was uncertain. Future research should be more rigorous and innovative in the way that risk factors are considered. This could be through statistical a... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5,649 | An increasing number of observational studies have reported associations between frailty and mental disorders, but the causality remains ambiguous | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9,123 | In this first proof-of-concept application of ML methods to predict childhood Posttraumatic Stress we were able to determine both predictive classification models for childhood PTSD and identify several causal variables. This set of techniques has great potential for enhancing the methodological toolkit in the field an... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
7,636 | To investigate the evidence for an association between climatic factors and infectious diseases, and to identify the most climate-sensitive diseases and vulnerable populations in the Arctic and subarctic region | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
23,564 | From the Web of Science Core Collection database, literature on the theme of hypertension and atrial fibrillation was retrieved. Subsequently, comprehensive bibliometric analyses were conducted across multiple dimensions utilizing software tools such as VOSviewer, Citespace, Pajek, Scimago Graphica, and ClusterProfiler... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
4,363 | Occupational exposure to respirable crystalline silica has been suggested by previous studies to increase the risk of kidney-related diseases. This study investigated the association between occupational exposure to crystalline silica and the risk of glomerulonephritis | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
25,620 | Our findings suggest that vedolizumab, although rarely, could cause AIN in patients with IBD. Awareness of laboratory findings and symptoms consistent with AIN, along with monitoring of the kidney function, could be warranted in patients with IBD treated with vedolizumab | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
19,665 | Although the cross sectional design limits causal inferences, the correlations between lacking health insurance and low rates of substance use treatment and healthcare use raise the possibility that increasing healthcare coverage might increase access to substance use treatment and other needed healthcare services for ... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
14,734 | Plastic surgery is a unique profession requiring astute minds capable of creative and "outside-the-box" thinking; traits we have learned in recent decades may be particularly keen in left-handed individuals, perhaps suggest a causal relationship to the conglomeration of a majority of left-handed plastic surgeons | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
16,933 | Migrants experience substantial changes in their neighborhood physical and social environments along their migration journeys, but little is known about how perceived changes in their neighborhood environment pre- and post-migration correlate with their mental health. Our aim was to examine the associations between rec... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
14,336 | Perceiving a personal risk for HIV infection is considered important for engaging in HIV prevention behaviour and often targeted in HIV prevention interventions. However, there is limited evidence for assumed causal relationships between risk perception and prevention behaviour and the degree to which change in behavio... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
23,734 | We carried out a retrospective cohort study with administrative health databases from Colombian population affiliated in the contributory health insurance scheme. We used an operative definition to select the cohort with diabetes. Incremental cost and cost ratio of diabetes were estimated using an inverse probability w... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
24,713 | To evaluate the effect of undernutrition on treatment success and sputum smear conversion among people with retreatment drug-susceptible TB in Kampala, Uganda | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
19,877 | Our work showed that the analgesic impact of EA is partly related to AMPK/mTOR pathway activation and autophagy induction in microglial cells, providing a potential therapeutic target for NP | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
22,351 | Our study suggests that higher DMI is associated with a reduced risk of KS disease. Future prospective studies are needed to clarify the causal relationship between DMI and KS disease | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
29,692 | Bias analysis provides a more complete picture of true uncertainty than conventional frequentist statistical analysis accompanied by a qualitative description of study limitations. The latter approach is likely to lead to overconfidence regarding the potential for causal associations, whereas the former safeguards agai... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1,418 | Prospective studies report associations between indicators of time spent sitting and obesity risk. Most studies use a single indicator of sedentary behavior and are unable to clearly identify whether sedentary behavior is a cause or a consequence of obesity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
12,731 | To assess the extent of reporting of non-adherence issues in published cluster trials and to establish which methods are currently being used for addressing non-adherence, if any, and whether clustering is accounted for in these | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
14,313 | The assessment of FAERS cases, combined with the temporal clustering of the Sentinel System cases suggest a possible causal relationship of DOACs and CSVV. Future efforts should characterize the risk of CSVV among the various DOAC users | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1,638 | Results of our study support the hypothesis that ETS exposure is independently associated with MetS and its individual components. Further large-scale studies with longitudinal design and objective assessment of ETS exposure are needed to elucidate the underlying mechanisms and the causal effects of passive smoking on ... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2,897 | In this study, we draw attention to a previously unexplored global inverse relationship between the prevalence of CMV and the incidence of BC, which suggests a potential oncoprotective role for this pathogen. Although the association itself does not imply causality, these data provide an intriguing possibility of obser... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
13,758 | This resource would be useful for studies that need to employ genome-wide association analyses involving Asian populations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5,534 | Our findings provide novel genetic evidence for bidirectional causal relationships between vegetarian-specific biomarkers and EC risk. These results enhance our understanding of EC pathogenesis and may inform future therapeutic strategies, particularly for vegetarian populations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10,652 | AIC lesions differentially affect the development and maintenance of the loss of control over cocaine intake, suggesting that the nature of the contribution of cocaine-associated interoceptive mechanisms changes over the course of escalation and may represent an important component of addiction | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2,626 | Associations between proteinuria and low-level urinary Cd should be interpreted with caution as they appear to be largely driven by diuresis, current smoking and probably also the co-excretion of Cd with plasma proteins | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2,043 | In our cases, we found that P. multiflorum Thunb could be hepatotoxic and could lead to severe drug-induced liver injury, and even death | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
4,481 | Adherence to a healthier lifestyle, as measured by the HLS, was significantly associated with lower atherogenic indices, highlighting its role in reducing cardiovascular risk. These results support integrating lifestyle interventions with cardiovascular prevention. Future studies should assess the causal impact of life... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
14,864 | Improved general health and reduced mental illness both improve the subjective financial situation of males and females. However, these affects diminish across older cohorts of males and females | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3,610 | In this paper, we describe a recent approach for constructing such weights that directly balances covariates while optimizing the stability of the resulting weighting estimator | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10,448 | Several functioning-related and symptom-related barriers and few socio-demographic factors were associated with physical activity among CRC survivors. Future interventions to promote physical activity among CRC survivors could benefit by taking into account functioning aspects and symptoms of cancer and its treatment, ... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3,834 | The results of this investigation reveal that leukemia closely relates to specific types of immune cells. Our findings provide a scientific basis for further investigations into factors that will improve immunotherapy | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
21,450 | A systematic review of RCTs of organ protection interventions targeting innate immune system activation did not resolve uncertainty as to the effectiveness of these treatments, or the role of innate immunity in organ injury following cardiac surgery | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
28,598 | Testosterone and smoking were positively correlated among mothers during their pregnancy and among adult daughters. Maternal prenatal cotinine had no direct effect on daughters' smoking; self-reported smoking in pregnancy did have a direct effect. Smoking among daughters during adolescence was determined by maternal pr... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10,960 | Hypertensive disorders of pregnancy are associated with accelerated cardiovascular aging and more diverse cardiovascular conditions than previously appreciated, including valvular heart disease. Cardiovascular risk after HDP is largely but incompletely mediated by development of chronic hypertension | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9,149 | To review the AEs of FMT and to address the concerns of safety during the procedure | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
22,453 | This study found digital media addiction as a predictor of decreased cognitive performance in children who use digital gadgets regularly. Although the cross-sectional design of the study precludes causal relationships from being determined, the study finding deserves further examination via longitudinal research | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
8,193 | This study does not provide compelling evidence for associations between most early-life factors and body composition in adolescence. However, possible associations with dietary patterns and physical inactivity in early childhood require further investigation in other cohorts that have direct measurements of adolescent... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
29,951 | Endothelial-dependent and endothelial-independent vascular responsiveness correlate with neurocognitive performance among older CVD patients, particularly in the attention-executive domain. While further study is needed to substantiate causal relationships, our data demonstrate that brachial responses serve as importan... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
28,934 | Although stroke is a leading cause of morbidity and mortality in Nigeria, there is no information on awareness of its warning signs. This study was designed to assess awareness of stroke warning signs in Nigerians at increased risk | stroke | morbidity in Nigeria | Intra | Explicit | stroke | mortality in Nigeria | Intra | Explicit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3,702 | EHRchitect streamlines the processing of large EHR datasets for research purposes. It facilitates extracting sequential event-based data, offering a highly flexible framework for configuring event and timeline parameters. The tool delivers temporal characteristics, patient demographics, and event metadata to support co... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
27,177 | Our MR analysis findings indicate a potential correlation between SSOE and a protective effect against lung cancer development. Further investigation is imperative to uncover the precise mechanistic link between them | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
24,916 | There is growing evidence that concentrations of environmental pollutants are previously associated with cardiovascular disease; however, it is unclear whether this association reflects a causal relationship | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
22,962 | Two hundred women completed a survey about their symptoms, level of pain, treatments, and the extent to which dysmenorrhea affected day-to-day obligations. Most questions were multiple-choice while others permitted several answer selections or were free response. The data was analyzed using JMP statistical software | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
17,800 | Worry, feeling worthless, equal status with husband and couple relationship are central symptoms of the family relationship-depressive symptoms network structure in pregnant women. Timely and systematic multilevel interventions targeting the central symptoms may be effective in alleviating the onset of depressive sympt... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
28,135 | Previous studies have suggested associations between conversion and many different clinical characteristics. This study investigates these findings in a prospective design including a control group | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
132 | Recent evidence suggests that diet modifies key biological factors associated with the development of depression; however, associations between diet quality and depression are not fully understood. We performed a systematic review to evaluate existing evidence regarding the association between diet quality and depressi... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
12,127 | HSV genital shedding measured by PCR analysis in swab specimens self-collected daily is an appropriate surrogate outcome for genital herpes lesions because it is in the causal pathway to recurrences | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5,631 | There is no causal relationship between female sex hormones and IBD, but male SHBG and testosterone are positively correlated with the risk of IBD and IBD promotes elevated levels of SHBG and testosterone in males, suggesting that sex hormones play different roles in IBD patients of different sexes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
8,785 | The articulatory loop employs sustained reciprocal propagation of neural activity across a network of cortical sites with strong neurophysiological connectivity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
28,477 | The commonest type of LV in Kuwait is primary cutaneous small vessel vasculitis. The most frequent laboratory abnormality associated with LV was increased ESR | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
21,894 | Non-fasting lipid assessment can help predict cardiovascular disease risks and is linked to multiple diseases, particularly diabetes. The significance of non-fasting lipid levels in routine screening and postprandial lipid tests for potential dyslipidemia has not been conclusively determined. Various new lipid-lowering... | Non-fasting lipid assessment | help predict cardiovascular disease risks | Intra | Implicit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
20,969 | This study demonstrates that IBD and its subtypes have a causal effect on HS, whereas HS does not affect IBD. Gut-skin axis interactions may help to understand this association. Nevertheless, further studies are needed to clarify the pathophysiology of the causal relationship between IBD and HS | IBD and its subtypes | HS | Intra | Explicit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
24,589 | These findings offer a nuanced understanding of the pathophysiological mechanisms underlying AD, thereby advancing the precision medicine paradigm in the clinical management of AD.Abbreviations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
29,640 | Dermatophytes, in particular Trichophyton violaceum, Trichophyton rubrum and Microsporum canis, are an important cause of tinea corporis in Libya. Malassezia furfur and Candida albicans are the most commonly encountered fungi in superficial mycoses | Trichophyton violaceum | tinea corporis in Libya | Intra | Explicit | Trichophyton rubrum | tinea corporis in Libya | Intra | Explicit | Microsporum canis | tinea corporis in Libya | Intra | Explicit | ||||||||||||||||||||||||||||||||||||||||||||||||||||
22,001 | This study is the first to demonstrate a case of human disease caused by a defect in centrosome reduction. We also uncovered a novel role for RTTN in perinatal cardiac development and identified a potential therapeutic strategy for centrosome-related iDCM. Future study aimed at identifying variants in centrosome compon... | defect in centrosome reduction | a case of human disease | Intra | Explicit | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
78 | Observational studies show breaking up prolonged sitting has beneficial associations with cardiometabolic risk markers, but intervention studies are required to investigate causality. We examined the acute effects on postprandial glucose and insulin levels of uninterrupted sitting compared with sitting interrupted by b... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
16,581 | This study is the first to document the differential risk of SJS/TEN for anticonvulsants in a real-world setting in Japan. Exposure to carbamazepine and lamotrigine was associated with an increased risk of SJS/TEN | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
13,240 | This study suggests the possibility of causal associations between victimization in childhood and depressive symptoms or MDD in adulthood, and the mediation of this association by neuroticism | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
27,487 | People with schizophrenia have a higher risk of mortality compared to the general population, which has not improved over time. The majority of premature deaths are due to comorbid physical diseases, driven by interrelated factors operating at the individual level, through health systems and influenced by social determ... | comorbid physical diseases | majority of premature deaths | Intra | Explicit |
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