pmid int64 10.6M 38.1M | title stringlengths 6 839 | abstract stringlengths 9 13.1k | authors sequence | journal_title stringlengths 2 239 | issn stringlengths 9 17 | publication_date stringclasses 26
values | doi stringlengths 12 65 | keywords sequence |
|---|---|---|---|---|---|---|---|---|
25,175,871 | NeuroHIV and use of addictive substances. | In the past three decades, substance abuse has been identified as a key comorbidity of human immunodeficiency virus-1 (HIV-1) infection. Many studies have found that the use and abuse of addictive substances hastens the progression of HIV-1 infection and HIV-associated neurocognitive disorders. Advances in highly activ... | [
"Sulie L Chang",
"Kaitlyn P Connaghan",
"Yufeng Wei",
"Ming D Li"
] | International review of neurobiology | 2162-5514 | 2014 | 10.1016/B978-0-12-801284-0.00013-0 | [
"NeuroHIV",
"Neuroinflammation",
"Substance abuse"
] |
27,995,511 | Zika Virus Disease for the Neurointensivist. | Zika virus (ZIKV) is a mosquito-borne and sexually transmitted flavivirus currently spreading throughout the Pacific and Western Hemisphere. ZIKV infection is often either asymptomatic or causes a self-limiting illness with symptoms such as rash, fever, myalgia, arthralgia, headache, or conjunctivitis. Rarely, ZIKV inf... | [
"Daniel M Pastula",
"Julia C Durrant",
"Daniel E Smith",
"J David Beckham",
"Kenneth L Tyler"
] | Neurocritical care | 1556-0961 | 2017 | 10.1007/s12028-016-0333-z | [
"Arbovirus",
"Encephalitis",
"Flavivirus",
"Guillain–Barré syndrome",
"Myelitis",
"Neurocritical care",
"Neurology",
"Seizures",
"Thrombocytopenia",
"Zika",
"Zika virus"
] |
27,510,731 | A community-based prospective cohort study of dengue viral infection in Malaysia: the study protocol. | Globally, dengue infections constitute a significant public health burden. In recent decades, Malaysia has become a dengue hyper-endemic country with the co-circulation of the four dengue virus serotypes. The cyclical dominance of sub-types contributes to a pattern of major outbreaks. The consequences can be observed i... | [
"Nowrozy Kamar Jahan",
"Mohtar Pungut Ahmad",
"Amreeta Dhanoa",
"Cheong Yuet Meng",
"Lau Wee Ming",
"Daniel D Reidpath",
"Pascale Allotey",
"Anuar Zaini",
"Maude Elvira Phipps",
"Quek Kia Fatt",
"Aman Bin Rabu",
"Rowther Sirajudeen",
"Ahmad AbdulBasitz Ahmad Fatan",
"Faidzal Adlee Ghafar",... | Infectious diseases of poverty | 2049-9957 | 2016 | 10.1186/s40249-016-0172-3 | [
"Community-based",
"Dengue",
"Health and demographic surveillance site",
"Prospective cohort study",
"Protocol",
"SEACO"
] |
24,418,539 | Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions. | Japanese encephalitis virus is one of the most common causes for epidemic viral encephalitis in humans and animals. Herein we demonstrated that cellular helicase DDX3 is involved in JEV replication. DDX3 knockdown inhibits JEV replication. The helicase activity of DDX3 is crucial for JEV replication. GST-pulldown and c... | [
"Chen Li",
"Ling-ling Ge",
"Peng-peng Li",
"Yue Wang",
"Juan-juan Dai",
"Ming-xia Sun",
"Li Huang",
"Zhi-qiang Shen",
"Xiao-chun Hu",
"Hassan Ishag",
"Xiang Mao"
] | Virology | 1096-0341 | 2014 | 10.1016/j.virol.2013.11.008 | [
"DEAD box RNA helicase DDX3",
"Japanese encephalitis virus",
"Un-translation region",
"Viral non-structural protein"
] |
34,635,185 | Paraneoplastic encephalomyeloradiculits with multiple autoantibodies against ITPR-1, GFAP and MOG: case report and literature review. | Recently, antibodies against the alpha isoform of the glial-fibrillary-acidic-protein (GFAPα) were identified in a small series of patients with encephalomyelitis. Coexisting autoantibodies (NMDA receptor, GAD65 antibodies) have been described in a few of these patients. We describe a patient with rapidly progressive e... | [
"Anna Cirkel",
"Klaus-Peter Wandinger",
"Claudia Ditz",
"Jan Leppert",
"Lars Hanker",
"Christoph Cirkel",
"Alexander Neumann",
"Jan Brocke",
"Romana Höftberger",
"Lars Komorowski",
"Sven Perner",
"Frank Leypoldt",
"Tobias Wagner-Altendorf",
"Thomas F Münte",
"Georg Royl"
] | Neurological research and practice | 2524-3489 | 2021 | 10.1186/s42466-021-00145-w | [
"Autoantibody",
"Encephalitis",
"Encephalomyelitis",
"Encephalomyeloradiculits",
"GFAP",
"ITPR-1",
"MOG",
"Multiple antibodies",
"Paraneoplastic"
] |
11,360,206 | Acute childhood encephalitis and Mycoplasma pneumoniae. | In a prospective 5-year study of children with acute encephalitis, evidence of Mycoplasma pneumoniae infection was demonstrated in 50 (31%) of 159 children. In 11 (6.9%) of these patients, M. pneumoniae was determined to be the probable cause of encephalitis on the basis of its detection in cerebrospinal fluid (CSF) by... | [
"A Bitnun",
"E L Ford-Jones",
"M Petric",
"D MacGregor",
"H Heurter",
"S Nelson",
"G Johnson",
"S Richardson"
] | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 1058-4838 | 2001 | 10.1086/320748 | [] |
35,069,540 | Encephalomyelitis Caused by <i>Balamuthia mandrillaris</i> in a Woman With Breast Cancer: A Case Report and Review of the Literature. | <i>Balamuthia mandrillaris</i> is one cause of a rare and severe brain infection called granulomatous amoebic encephalitis (GAE), which has a mortality rate of >90%. Diagnosis of <i>Balamuthia</i> GAE is difficult because symptoms are non-specific. Here, we report a case of <i>Balamuthia</i> amoebic encephalomyelitis (... | [
"Juan Hu",
"Yiqi Zhang",
"Yongwei Yu",
"Huili Yu",
"Siruo Guo",
"Ding Shi",
"Jianqin He",
"Chi Hu",
"Jiqi Yang",
"Xueling Fang",
"Yonghong Xiao"
] | Frontiers in immunology | 1664-3224 | 2021 | 10.3389/fimmu.2021.768065 | [
"Balamuthia mandrillaris",
"T-cell receptor",
"encephalitis",
"encephalomyelitis",
"next-generation sequencing"
] |
15,048,893 | Glutamate receptor antagonists protect from virus-induced neural degeneration. | Neuronal damage during acute viral encephalomyelitis can result directly from virus infection or indirectly from the host immune response to infection. In neurodegenerative diseases and stroke, neuronal death also can result from excess release of excitatory amino acid neurotransmitters, such as glutamate. To determine... | [
"Jennifer L Nargi-Aizenman",
"Michael B Havert",
"Ming Zhang",
"David N Irani",
"Jeffrey D Rothstein",
"Diane E Griffin"
] | Annals of neurology | 0364-5134 | 2004 | 10.1002/ana.20033 | [] |
30,291,563 | Rapidly progressive encephalopathy caused by Coxsackie meningoencephalitis in an elderly male. | Enteroviruses and Coxsackie viruses are common causes of aseptic meningitis and encephalitis in children. These infections usually have a benign, self-limited course. However, they can have a florid presentation in immunocompromised patients, such as neonates, patients exposed to immunosuppressive drugs, such as transp... | [
"Masoom Desai",
"Melissa Motta"
] | Journal of neurovirology | 1538-2443 | 2018 | 10.1007/s13365-018-0676-7 | [
"Coxsackievirus",
"Encephalitis",
"Enterovirus",
"Meningitis",
"Meningoencephalitis",
"Meningoencephalitis in an immunocompetent male",
"Rapidly progressive encephalopathy"
] |
28,056,425 | FCD Type II and mTOR pathway: Evidence for different mechanisms involved in the pathogenesis of dysmorphic neurons. | Type II focal cortical dysplasia (FCD II) is a malformation of cortical development, frequently associated with intractable epilepsy, characterised by cortical dyslamination, dysmorphic neurons (DNs) and balloon cells (BCs). We investigated the expression of pS6 (downstream target) and pPDK1-pAkt (upstream targets) as ... | [
"Laura Rossini",
"Flavio Villani",
"Tiziana Granata",
"Laura Tassi",
"Giovanni Tringali",
"Francesco Cardinale",
"Eleonora Aronica",
"Roberto Spreafico",
"Rita Garbelli"
] | Epilepsy research | 1872-6844 | 2017 | 10.1016/j.eplepsyres.2016.12.002 | [
"Epilepsy surgery",
"Focal cortical dysplasia",
"inflammation",
"mTOR pathway",
"pI3K-Akt pathway",
"pS6"
] |
16,931,137 | Presence of rabies specific immune complexes in cerebro-spinal fluid can help in ante-mortem diagnosis of human paralytic rabies. | Human rabies presents in two clinical forms, viz. furious or encephalitic and paralytic. Clinical diagnosis of paralytic form is difficult and requires laboratory confirmation. Presently available diagnostic techniques are not very sensitive for ante-mortem confirmation of rabies. | [
"K Muhamuda",
"S N Madhusudana",
"V Ravi",
"A Desai"
] | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | 1386-6532 | 2006 | 10.1016/j.jcv.2006.06.010 | [] |
24,203,667 | [Encephalitis due to the Epstein-Barr virus: a description of a clinical case and review of the literature]. | INTRODUCTION. Infection by the Epstein-Barr virus (EBV) -either as a primary infection, a reactivation or an active chronic infection- can give rise to several clinical forms of involvement of the central nervous system. We report a case of encephalitis due to EBV produced by viral reactivation in an immunocompetent pa... | [
"Johanna Barón",
"Sonia Herrero-Velázquez",
"Marina Ruiz-Piñero",
"M Isabel Pedraza",
"Silvia Rojo-Rello",
"Ángel Luis Guerrero-Peral"
] | Revista de neurologia | 1576-6578 | 2013 | No DOI available | [] |
15,221,068 | [Case of inflammatory vasculopathy and encephalopathy caused by treatment with tacrolimus]. | The case of inflammatory vasculopathy and encephalopathy caused by treatment with tacrolimus is reported. This 49-year-old woman developed progressive gait ataxia and right-sided hemiparesis after 7 years of tacrolimus therapy for focal sclerosing glomerulonephritis. MRI presented multifocal cerebral lesions with contr... | [
"Adrian Ringelstein",
"Katja Bongs",
"Burkhard Sorge-Hädicke",
"Peter Berlit"
] | Der Nervenarzt | 1433-0407 | 2005 | 10.1007/s00115-004-1744-1 | [] |
25,296,876 | [Clinical course of recovery from cognitive dysfunction in a patient with anti-N-methyl-D-aspartate receptor encephalitis]. | Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder, which occurs commonly in young women and is often associated with ovarian teratomas. We report the case of a patient with this disease, who exhibited cognitive deficits, and describe the clinical course of recovery from cognitive dysfunct... | [
"Chikako Asai",
"Akiyoshi Morinaga",
"Kumiko Yamamoto",
"Toru Imamura"
] | Brain and nerve = Shinkei kenkyu no shinpo | 1881-6096 | 2014 | 10.11477/mf.1416200013 | [] |
23,695,498 | Punctate lesion pattern suggestive of perivascular inflammation in acute natalizumab-associated progressive multifocal leukoencephalopathy: productive JC virus infection or preclinical PML-IRIS manifestation? | No abstract available | [
"Mike P Wattjes",
"Lonneke Verhoeff",
"Willemijn Zentjens",
"Joep Killestein",
"Erik T van Munster",
"Frederik Barkhof",
"Jeroen J J van Eijk"
] | Journal of neurology, neurosurgery, and psychiatry | 1468-330X | 2013 | 10.1136/jnnp-2013-304986 | [
"Infectious Diseases",
"MRI",
"Multiple Sclerosis"
] |
30,759,326 | Reversible myoclonus-ataxia encephalitis related to anti-mGLUR1 autoantibodies. | No abstract available | [
"Cedric Gollion",
"Julia Dupouy",
"Meryl Roberts",
"Marion Simonetta-Moreau",
"Christine Brefel Courbon",
"Olivier Rascol",
"Jerome Honnorat",
"Fabienne Ory Magne"
] | Movement disorders : official journal of the Movement Disorder Society | 1531-8257 | 2019 | 10.1002/mds.27634 | [] |
21,507,219 | Acute urinary retention in a 23-year-old woman with mild encephalopathy with a reversible splenial lesion: a case report. | Patients with clinically mild encephalitis/encephalopathy with a reversible splenial lesion present with relatively mild central nervous system disturbances. Although the exact etiology of the condition remains poorly understood, it is thought to be associated with infective agents. We present a case of a patient with ... | [
"Makiko Kitami",
"Shin-Ichiro Kubo",
"Shinichiro Nakamura",
"Shinji Shiozawa",
"Hideyuki Isobe",
"Yoshiaki Furukawa"
] | Journal of medical case reports | 1752-1947 | 2011 | 10.1186/1752-1947-5-159 | [] |
20,062,542 | Intracranial administration of P gene siRNA protects mice from lethal Chandipura virus encephalitis. | In parts of India, Chandipura Virus (CHPV) has emerged as an encephalitis causing pathogen in both epidemic and sporadic forms. This pediatric disease follows rapid course leading to 55-75% mortality. In the absence of specific treatment, effectiveness of RNA interference (RNAi) was evaluated. | [
"Satyendra Kumar",
"Vidya A Arankalle"
] | PloS one | 1932-6203 | 2010 | 10.1371/journal.pone.0008615 | [] |
23,820,312 | Non-convulsive status epilepticus associated with glutamic acid decarboxylase antibody. | Autoimmune encephalitis associated with glutamic acid decarboxylase antibodies (GAD-Ab) often presents with treatment-resistant partial seizures, as well as other central nervous system symptoms. In contrast to several other well-characterized autoantibodies, GAD-Ab has very rarely been associated with status epileptic... | [
"Ugur Cikrikçili",
"Canan Ulusoy",
"Selin Turan",
"Senay Yildiz",
"Basar Bilgiç",
"Hasmet Hanagasi",
"Betül Baykan",
"Erdem Tüzün",
"Hakan Gürvit"
] | Clinical EEG and neuroscience | 1550-0594 | 2013 | 10.1177/1550059412459330 | [
"antibody",
"autoimmunity.",
"epilepsy",
"glutamic acid decarboxylase",
"non-convulsive status"
] |
18,032,598 | Utilization of complement-dependent cytotoxicity to measure low levels of antibodies: application to nonstructural protein 1 in a model of Japanese encephalitis virus. | Enzyme-linked immunosorbent assay (ELISA) and related assays are representative of methods currently used for antibody tests. However, they occasionally produce nonspecific reactions, thus making it difficult to reliably measure low levels of specific antibodies. To find a test method that minimizes nonspecific reactio... | [
"Eiji Konishi",
"Yoko Kitai",
"Takashi Kondo"
] | Clinical and vaccine immunology : CVI | 1556-679X | 2008 | 10.1128/CVI.00347-07 | [] |
31,330,214 | Shape effect in active targeting of nanoparticles to inflamed cerebral endothelium under static and flow conditions. | Endothelial cells represent the first biological barrier for compounds, including nanoparticles, administered via the intravascular route. In the case of ischemic stroke and other vascular diseases, the endothelium overexpresses specific markers, which can be used as molecular targets to facilitate drug delivery and im... | [
"A Da Silva-Candal",
"T Brown",
"V Krishnan",
"I Lopez-Loureiro",
"P Ávila-Gómez",
"A Pusuluri",
"A Pérez-Díaz",
"C Correa-Paz",
"P Hervella",
"J Castillo",
"S Mitragotri",
"F Campos"
] | Journal of controlled release : official journal of the Controlled Release Society | 1873-4995 | 2019 | 10.1016/j.jconrel.2019.07.026 | [
"Active targeting",
"Brain",
"Inflammation",
"Shape"
] |
34,671,714 | Peritoneal dialysis improves quality-of-life in a left ventricular assist device destination therapy patient-a case report. | Progressive renal insufficiency is frequent in heart failure patients with a left ventricular assist device (LVAD). The optimal strategy for long-term dialysis in LVAD patients and its effect on quality-of-life in these patients remain to be determined. | [
"Claire J Koppel",
"Jacqueline T Jonker",
"Wieneke M Michels",
"Saskia L M A Beeres"
] | European heart journal. Case reports | 2514-2119 | 2021 | 10.1093/ehjcr/ytab307 | [
"Case report",
"Heart failure",
"Left ventricular assist device",
"Peritoneal dialysis",
"Quality-of-life",
"Renal replacement therapy"
] |
19,428,026 | Progressive multifocal leukoencephalopathy in a patient with Franklin disease and hypogammaglobulinemia. | We report an association between histologically confirmed progressive multifocal leukoencephalopathy (PML) and an extremely rare humoral immunodeficiency disease, Franklin disease. In our patient, clinical presentation has been typical and prompted us, together with radiological findings, to perform a brain biopsy to c... | [
"Giorgio Tasca",
"Raffaele Iorio",
"Umberto Basile",
"Libero Lauriola",
"Raffaele Tartaglione",
"Massimiliano Mirabella",
"Enzo Ricci",
"Mario Sabatelli"
] | Journal of the neurological sciences | 1878-5883 | 2009 | 10.1016/j.jns.2009.04.035 | [] |
20,618,662 | Mosquito (Diptera: Culicidae) fauna in an area endemic for West Nile virus. | Mosquito collections with CDC light traps using dry ice and pigeon-baited traps were carried out in south Moravia (Czech Republic) from April to October in 2007 and 2008 at two study sites. In 2007, 11 two-day captures were carried out in two-week intervals, and 1,490 female mosquitoes of nine species were caught. In 2... | [
"O Sebesta",
"J Halouzka",
"Z Hubálek",
"Z Juricová",
"I Rudolf",
"S Sikutová",
"P Svobodová",
"P Reiter"
] | Journal of vector ecology : journal of the Society for Vector Ecology | 1948-7134 | 2010 | 10.1111/j.1948-7134.2010.00042.x | [] |
25,558,588 | [A case of acute encephalitis with refractory repetitive partial seizures successfully controlled by very-high-dose phenobarbital therapy found in a boy]. | We experienced a case of acute encephalitis with refractory, repetitive partial seizures (AERRPS) found in an 8-year-old boy. Convulsive status epilepticus developed at the onset, which was intractable to the treatment with intravenous thiopental sodium even at the maximum dose of 9 mg/kg/hr. Since the adverse effect d... | [
"Seiji Watanabe",
"Yoshinori Okumura",
"Hideo Aiba"
] | No to hattatsu = Brain and development | 0029-0831 | 2014 | No DOI available | [] |
24,342,133 | Impact of drought on vector-borne diseases--how does one manage the risk? | This article aimed to review all literature on drought and vector-borne disease to enable an assessment of the possible impact of drought on the changing risk of vector-borne diseases in the UK. | [
"L Brown",
"J Medlock",
"V Murray"
] | Public health | 1476-5616 | 2014 | 10.1016/j.puhe.2013.09.006 | [
"Drought",
"Mosquitoes",
"Re-wetting",
"Ticks",
"Vector-borne diseases"
] |
36,005,147 | Basic Analysis of the Cerebrospinal Fluid: An Important Framework for Laboratory Diagnostics of the Impairment of the Central Nervous System. | Laboratory analysis of basic cerebrospinal fluid (CSF) parameters is considered as essential for any CSF evaluation. It can provide rapidly very valuable information about the status of the central nervous system (CNS). Our retrospective study evaluated parameters of basic CSF analysis in cases of either infectious or ... | [
"Petr Kelbich",
"Karel Hrach",
"Jan Spicka",
"Petr Vachata",
"Tomas Radovnicky",
"Eva Hanuljakova",
"Jan Krejsek"
] | Current issues in molecular biology | 1467-3045 | 2022 | 10.3390/cimb44080251 | [
"aspartate aminotransferase",
"blood-brain barrier",
"blood-cerebrospinal fluid barrier",
"cerebrospinal fluid",
"coefficient of energy balance",
"cytological-energy analysis"
] |
23,098,914 | The human and animal health impacts of introduction and spread of an exotic strain of West Nile virus in Australia. | Vector-borne diseases can have substantial impacts on human and animal health, including major epidemics. West Nile virus (WNV) is of particular international importance due to its recent emergence and impact in the Western Hemisphere. Despite the presence of a sub-type of WNV (Kunjin virus, KUN) in Australia, a potent... | [
"Marta Hernández-Jover",
"Sharon Roche",
"Michael P Ward"
] | Preventive veterinary medicine | 1873-1716 | 2013 | 10.1016/j.prevetmed.2012.09.018 | [] |
12,192,246 | Cognitive dysfunction in neuropsychiatric systemic lupus erythematosus. | Neuropsychiatric syndromes associated with systemic lupus erythematosus are common, but diverse in etiology and presentation. Cognitive dysfunction is prevalent among these syndromes, but exhibit a significant degree of heterogeneity both within and between patient variability. Earlier studies of SLE-associated cogniti... | [
"Melanie J Harrison",
"Lisa D Ravdin"
] | Current opinion in rheumatology | 1040-8711 | 2002 | 10.1097/00002281-200209000-00005 | [] |
20,338,734 | [Hemorrhagic lesion of the corpus callosum in influenza-associated encephalitis]. | We describe a rare case of Influenza B-associated encephalopathy with hemorrhagic lesions of the corpus callosum. A 12-year-old Caucasian girl presented a 24-h fever followed by partial seizure, secondarily generalized, and disturbance of consciousness. Magnetic resonance imaging on Day 2 of her illness showed two hemo... | [
"M Burillon",
"E Cheuret",
"Y Chaix"
] | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie | 1769-664X | 2010 | 10.1016/j.arcped.2010.02.010 | [] |
35,276,731 | The Impact of Adulticide on Culex Abundance and Infection Rate in North Shore of Cook County, Illinois. | Mosquito surveillance is critical to reduce the risk of West Nile virus (WNV) transmission to humans. In response to surveillance indicators such as elevated mosquito abundance or increased WNV levels, many mosquito control programs will perform truck-mounted ultra-low volume (ULV) adulticide application to reduce the ... | [
"Danielle Sass",
"Bo Li",
"Mark Clifton",
"Justin Harbison",
"Christopher Xamplas",
"Rebecca Smith"
] | Journal of the American Mosquito Control Association | 1943-6270 | 2022 | 10.2987/21-7036 | [
"Adulticide application",
"West Nile virus",
"fused ridge",
"generalized additive model",
"truck-mounted ULV"
] |
24,827,765 | West Nile virus infection in kidney and pancreas transplant recipients in the Dallas-Fort Worth Metroplex during the 2012 Texas epidemic. | In 2012, the United States experienced one of its worst West Nile virus (WNV) epidemics, reporting 5,387 human cases and final death toll of 243. Texas was at the epicenter of the outbreak, with 1,875 reported cases and 89 deaths that year. The Texas outbreak centered mainly in the Dallas-Fort Worth area where 30 death... | [
"Angelito F Yango",
"Bernard V Fischbach",
"Marlon Levy",
"Arun Chandrakantan",
"Valerie Tan",
"Cedric Spak",
"Larry Melton",
"Kim Rice",
"Yousri Barri",
"Arthi Rajagopal",
"Goran Klintmalm"
] | Transplantation | 1534-6080 | 2014 | 10.1097/01.TP.0000438621.81686.ab | [] |
32,774,660 | An atypical case of febrile infection-related epilepsy syndrome following acute encephalitis: impact of physiotherapy in regaining locomotor abilities in a patient with neuroregression. | Encephalitis refers to inflammation of the brain parenchyma. It is potentially life-threatening with the highest incidence and severity in younger children. Febrile infection-related epilepsy syndrome (FIRES) is a condition, in which a child develops a nonspecific febrile illness that may not persist when the initial s... | [
"Chanan Goyal",
"Waqar M Naqvi",
"Arti Sahu"
] | The Pan African medical journal | 1937-8688 | 2020 | 10.11604/pamj.2020.36.101.23855 | [
"Post encephalitis sequelae",
"neurodevelopmental treatment",
"sensory integration"
] |
35,412,386 | Identification and Genomic Characterization of Parvovirus B19V Genotype 3 Viruses from Cases of Meningoencephalitis in West Bengal, India. | Brain infections are a major public health problem in India and other parts of the world, causing both mortality and lifelong disability. Even after a thorough investigation, many cases remain without an etiological diagnosis. Primate erythroparvovirus 1 (B19V) has been identified as a pathogen associated with undiagno... | [
"Chitra Pattabiraman",
"Pramada Prasad",
"Sampada Sudarshan",
"Anson K George",
"Darshan Sreenivas",
"Risha Rasheed",
"Ayushman Ghosh",
"Ananya Pal",
"Shafeeq K Shahul Hameed",
"Bhaswati Bandyopadhyay",
"Anita Desai",
"Ravi Vasanthapuram"
] | Microbiology spectrum | 2165-0497 | 2022 | 10.1128/spectrum.02251-21 | [
"B19V",
"India",
"brain infections",
"meningoencephalitis",
"parvovirus",
"pathogen genomics",
"public health",
"virology"
] |
25,869,034 | Roe deer sera used for TBE surveillance in Austria. | A large majority of Austrian citizens are aware of tick-borne encephalitis (TBE), consequently reflected by a high vaccination rate of 85%. In return, risk assessment and disease mapping on human cases might be hampered due to high and inhomogeneous vaccination rates and travel habitats of humans. The roe deer was used... | [
"Georg Gerhard Duscher",
"Monika Wetscher",
"Raphaela Baumgartner",
"Gernot Walder"
] | Ticks and tick-borne diseases | 1877-9603 | 2015 | 10.1016/j.ttbdis.2015.03.018 | [
"Risk map",
"Roe deer",
"TBE"
] |
18,050,710 | [Molecular epidemiology of tick-borne encephalitis]. | The review presents information on the development of studies into the molecular epidemiology of tick-borne encephalitis (TBE) in Russia and foreign countries. The existence of three major virus genotypes has been established by various techniques, such as genomic fragment sequencing, molecular hybridization using geno... | [
"V I Zlobin",
"M M Verkhozina",
"T V Demina",
"Iu P Dzhioev",
"R V Adel'shin",
"I V Kozlova",
"S I Belikov",
"M A Khasnatinov",
"G A Danchinova",
"E I Isaeva",
"A E Grishechkin"
] | Voprosy virusologii | 0507-4088 | 2007 | No DOI available | [] |
17,545,649 | Serological evidence for West Nile virus infection in horses in Croatia. | No abstract available | [
"J Madić",
"G Savini",
"A Di Gennaro",
"F Monaco",
"B Jukić",
"S Kovac",
"N Rudan",
"E Listes"
] | The Veterinary record | 0042-4900 | 2007 | 10.1136/vr.160.22.772 | [] |
22,515,699 | Inflammation and clinical presentation in neurodegenerative disease: a volatile relationship. | A proposed immune mechanism that potentially modifies or exacerbates neurodegenerative disease presentation in older adults has received considerable attention in the past decade, with recent studies demonstrating a strong link between pro-inflammatory markers and neurodegeneration. The overarching aim of the following... | [
"Brianne Magouirk Bettcher",
"Joel H Kramer"
] | Neurocase | 1465-3656 | 2013 | 10.1080/13554794.2011.654227 | [] |
28,627,763 | Suspected Methadone Toxicity: from Hospital to Autopsy Bed. | High mortality rates have been reported for methadone in both adults and children. We aimed to determine the pattern of toxicity, possible underlying diseases and treatment challenges in patients referred to our centre with early diagnosis of methadone toxicity and who later died. Medical files of all methadone-poisone... | [
"Jaber Gharehdaghi",
"Asieh Takalloo-Bakhtiari",
"Hossein Hassanian-Moghaddam",
"Nasim Zamani",
"Mohammad-Javad Hedayatshode"
] | Basic & clinical pharmacology & toxicology | 1742-7843 | 2017 | 10.1111/bcpt.12831 | [] |
18,632,953 | D2: major subgenotype of hepatitis B virus in Russia and the Baltic region. | Complete or almost complete hepatitis B virus (HBV) genomes were sequenced for 13 genotype A and 42 genotype D strains from the former USSR. The strains were classifiable within subgenotypes A2, D1, D2 and D3. Comparison of the deduced gene products for the four ORFs of 89 genotype D strains revealed 27 subgenotype-spe... | [
"Tatjana Tallo",
"Valentina Tefanova",
"Ljudmilla Priimägi",
"Jelena Schmidt",
"Olga Katargina",
"Michail Michailov",
"Sergey Mukomolov",
"Lars Magnius",
"Heléne Norder"
] | The Journal of general virology | 0022-1317 | 2008 | 10.1099/vir.0.83660-0 | [] |
33,145,945 | Longitudinal measurement of cerebrospinal fluid neurofilament light in anti-N-methyl-D-aspartate receptor encephalitis. | Biomarkers reflecting the course of patients suffering from anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDARE) are urgently needed. Neurofilament light chains (NfL) have been studied as potential markers for neuroaxonal injury mainly in neuroinflammatory diseases, but so far there have been only in a few sma... | [
"Stefan Macher",
"Tobias Zrzavy",
"Romana Höftberger",
"Patrick Altmann",
"Ekatarina Pataraia",
"Fritz Zimprich",
"Thomas Berger",
"Paulus Rommer"
] | European journal of neurology | 1468-1331 | 2021 | 10.1111/ene.14631 | [
"anti-N-methyl-D-aspartate receptor encephalitis",
"encephalitis",
"neurodegeneration",
"neurofilament light"
] |
29,718,438 | Asian travel: from the rare to the difficult. | No abstract available | [
"Tristan P Learoyd"
] | Journal of travel medicine | 1708-8305 | 2018 | 10.1093/jtm/tay015 | [] |
19,483,524 | Human parechovirus-3 infection: emerging pathogen in neonatal sepsis. | Human parechovirus-3 (HPeV-3) is an emerging pathogen that has been described as a cause of neonatal sepsis. Human parechoviruses are a family of viruses closely related to enteroviruses; however, enteroviral PCR will not detect HPeVs. We present clinical details of neonatal meningoencephalitis and hepatitis-coagulopat... | [
"Rebecca E Levorson",
"Barbara A Jantausch",
"Bernhard L Wiedermann",
"Hans M L Spiegel",
"Joseph M Campos"
] | The Pediatric infectious disease journal | 0891-3668 | 2009 | 10.1097/INF.0b013e318194596a | [] |
33,472,038 | Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation. | Tau is a major driver of neurodegeneration and is implicated in over 20 diseases. Tauopathies are characterized by synaptic loss and neuroinflammation, but it is unclear if these pathological events are causally linked. Tau binds to Synaptogyrin-3 on synaptic vesicles. Here, we interfered with this function to determin... | [
"Pablo Largo-Barrientos",
"Nuno Apóstolo",
"Eline Creemers",
"Zsuzsanna Callaerts-Vegh",
"Jef Swerts",
"Caitlin Davies",
"Joseph McInnes",
"Keimpe Wierda",
"Bart De Strooper",
"Tara Spires-Jones",
"Joris de Wit",
"Valerie Uytterhoeven",
"Patrik Verstreken"
] | Neuron | 1097-4199 | 2021 | 10.1016/j.neuron.2020.12.016 | [
"Tau",
"microglia",
"neuroinflammation",
"synapses",
"synaptic loss",
"synaptic plasticity",
"working memory"
] |
17,079,283 | Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses. | The interferon (IFN)-stimulated genes (ISGs) ISG-49, ISG-54, and ISG-56 are highly responsive to viral infection, yet the regulation and function of these genes in vivo are unknown. We examined the simultaneous regulation of these ISGs in the brains of mice during infection with either lymphocytic choriomeningitis viru... | [
"Christie Wacher",
"Marcus Müller",
"Markus J Hofer",
"Daniel R Getts",
"Regina Zabaras",
"Shalina S Ousman",
"Fulvia Terenzi",
"Ganes C Sen",
"Nicholas J C King",
"Iain L Campbell"
] | Journal of virology | 0022-538X | 2007 | 10.1128/JVI.01167-06 | [] |
25,146,376 | Expression of the mannose receptor CD206 in HIV and SIV encephalitis: a phenotypic switch of brain perivascular macrophages with virus infection. | We examined the expression of the mannose receptor CD206 by perivascular macrophages (PVM) in normal human and monkey brains and in brains of HIV-infected humans and of monkeys infected with simian immunodeficiency virus (SIV). Depletion of brain PVM in SIV-infected monkeys by intrathecal injection of liposome-encapsul... | [
"Gerard E Holder",
"Christopher M McGary",
"Edward M Johnson",
"Rubo Zheng",
"Vijay T John",
"Chie Sugimoto",
"Marcelo J Kuroda",
"Woong-Ki Kim"
] | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology | 1557-1904 | 2014 | 10.1007/s11481-014-9564-y | [] |
12,905,146 | Fatal human rabies caused by European bat Lyssavirus type 2a infection in Scotland. | We wish to report the first recorded case of indigenous human rabies caused by a bat bite in the United Kingdom in 100 years. This instructive case report highlights a number of key lessons: first, bites from insectivorous bats indiginous to the United Kingdom can cause rabies in humans; second, rabies immunization is ... | [
"D Nathwani",
"P G McIntyre",
"K White",
"A J Shearer",
"N Reynolds",
"D Walker",
"G V Orange",
"A R Fooks"
] | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 1537-6591 | 2003 | 10.1086/376641 | [] |
23,955,394 | Unsuccessful cyclosporine plus prednisolone therapy for autoimmune meningoencephalitis in three dogs. | A 4-year-old female Maltese (case 1), a 9-year-old castrated male shih tzu (case 2) and 2-year-old female Pomeranian (case 3) presented with neurological signs, such as head tilt, ataxia, circling and paresis. The three cases were tentatively diagnosed as having meningoencephalitis of unknown etiology based on computed... | [
"Dong-In Jung",
"Hee-Chun Lee",
"Jeongim Ha",
"Hae-Won Jung",
"Joon-Hyeok Jeon",
"Jong-Hyun Moon",
"Jae-Hoon Lee",
"Na-Hyun Kim",
"Jung-Hyang Sur",
"Byeong-Teck Kang",
"Kyu-Woan Cho"
] | The Journal of veterinary medical science | 1347-7439 | 2013 | 10.1292/jvms.12-0503 | [] |
24,995,204 | Dancing eyes dancing feet syndrome-a report of two cases. | Opsoclonus Myoclonus (OMS) is a rare neurological disorder which appears to be the result of an autoimmune dysfunction. It is an extremely rare condition, affecting as few as 1 in 10,000,000 people every year. It affects 2 to 3% of children. Opsoclonus Myoclonus, which manifests itself as post infectious encephalopathy... | [
"P Jasminekalyani",
"S Saravanan",
"Sriramakrishnan V",
"Radha M"
] | Journal of clinical and diagnostic research : JCDR | 2249-782X | 2014 | 10.7860/JCDR/2014/7184.4339 | [
"Autoimmune disorder",
"Opsoclonus myoclonus",
"Paraneoplastic syndrome",
"Post infectious encephalopathy"
] |
25,343,330 | Lidocaine treatment in refractory status epilepticus resulting from febrile infection-related epilepsy syndrome: a case report and follow-up. | We report the management of refractory status epilepticus (SE) by using continuous intravenous infusions of lidocaine in a previously healthy 15-year-old girl with a "catastrophic encephalopathy" in whom a diagnosis of febrile infection-related epilepsy syndrome was supposed. One week after a banal pharyngitis and feve... | [
"Giorgio Capizzi",
"Roberta Vittorini",
"Francesca Torta",
"Chiara Davico",
"Elena Rainò",
"Alessandra Conio",
"Annalisa Longobardo",
"Eleonora Briatore",
"Barbara Podestà",
"Stefano Calzolari"
] | Neuropediatrics | 1439-1899 | 2015 | 10.1055/s-0034-1389898 | [] |
37,344,220 | The impact of climatic conditions on the dynamics of tick-borne encephalitis in Slovakia in 2012-2016. | The main aim of our work was to analyse the development of the dynamics of tick-borne encephalitis (TBE) in connection with climatic conditions in Slovakia in 2012-2016. | [
"V Hudáčková",
"J Pekarčíková",
"B Peťko",
"K Mikulová",
"P Sivčo",
"M Rusňák"
] | Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne | 1210-7913 | 2023 | No DOI available | [
"Tick-borne encephalitis",
"altitude",
"climate",
"seasonality",
"standardized morbidity"
] |
15,000,552 | Serum S100B levels in patients with cerebral and extracerebral infectious disease. | S100B has been shown to increase in cerebrospinal fluid (CSF) and serum after various neurological diseases and it has been postulated that S100B could serve as a serum marker for brain damage. However there is limited information concerning serum S100B levels in infectious diseases of the brain. Blood samples were col... | [
"Johan Undén",
"Bertil Christensson",
"Johan Bellner",
"Christer Alling",
"Bertil Romner"
] | Scandinavian journal of infectious diseases | 0036-5548 | 2004 | 10.1080/00365540310017294 | [] |
29,707,126 | HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute viral encephalitis. | The HLA genes, as well as the innate immune KIR genes, are considered relevant determinants of viral outcomes but no study, to our knowledge, has evaluated their role in the clinical setting of acute viral encephalitis. | [
"Antonino Tuttolomondo",
"Claudia Colomba",
"Danilo Di Bona",
"Alessandra Casuccio",
"Domenico Di Raimondo",
"Giuseppe Clemente",
"Valentina Arnao",
"Rosaria Pecoraro",
"Paolo Ragonese",
"Anna Aiello",
"Giulia Accardi",
"Rosario Maugeri",
"Carlo Maida",
"Irene Simonetta",
"Vittoriano Del... | Oncotarget | 1949-2553 | 2018 | 10.18632/oncotarget.24778 | [
"HLA",
"KIRs",
"encephalitis"
] |
20,130,066 | A chimeric alphavirus replicon particle vaccine expressing the hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques from measles. | Measles remains a major cause of child mortality, in part due to an inability to vaccinate young infants with the current live attenuated virus vaccine (LAV). To explore new approaches to infant vaccination, chimeric Venezuelan equine encephalitis/Sindbis virus (VEE/SIN) replicon particles were used to express the hema... | [
"Chien-Hsiung Pan",
"Catherine E Greer",
"Debra Hauer",
"Harold S Legg",
"Eun-Young Lee",
"M Jeff Bergen",
"Brandyn Lau",
"Robert J Adams",
"John M Polo",
"Diane E Griffin"
] | Journal of virology | 1098-5514 | 2010 | 10.1128/JVI.01566-09 | [] |
27,247,185 | [Herpes simplex encephalitis without cerebrospinal fluid pleocytosis in a patient with bullous pemphigoid: a case report]. | A 78-year-old woman was diagnosed with bullous pemphigoid 2 months ago, and she had been treated with steroid and plasmapheresis. She developed sudden fever, vomiting, disorientation, and abnormal behavior. Diffusion weighted images and fluid-attenuated inversion recovery (FLAIR) magnetic resonance (MR) images showed h... | [
"Yoshitsugu Nakamura",
"Kensuke Kakiuti",
"Hiroki Tani",
"Hideto Nakajima",
"Fumiharu Kimura",
"Toshiaki Hanafusa"
] | Rinsho shinkeigaku = Clinical neurology | 1882-0654 | 2016 | 10.5692/clinicalneurol.cn-000870 | [] |
35,670,686 | Interstitial granulomatous dermatitis and concurrent immunotherapy associated encephalitis with nivolumab and ipilimumab. | Immune-related adverse events (irAEs) are common in patients receiving immune checkpoint inhibitors for metastatic melanoma and other advanced malignancies. Cutaneous, gastrointestinal, and endocrine (thyroid) irAEs are most prevalent, whereas neurologic irAEs are rare. We present a 73-year-old man with dementia and me... | [
"Caroline T Starling",
"Alison A Messer",
"Anne Kleiman",
"Jennifer L McQuade",
"Isabella C Glitza",
"Carlos Antonio Torres-Cabala",
"Meghan Heberton"
] | Dermatology online journal | 1087-2108 | 2022 | 10.5070/D328257399 | [] |
33,610,347 | Clinical description of the broad range of neurological presentations of COVID-19: A retrospective case series. | Neurological disorders associated with SARS-CoV-2 infection represent a clinical challenge because they encompass a broad neurological spectrum and may occur before the diagnosis of COVID-19. | [
"L Cleret de Langavant",
"A Petit",
"Q T R Nguyen",
"T Gendre",
"J Abdelhedi",
"A Djellaoui",
"L Seddik",
"L Lim",
"F Faugeras",
"H Salhi",
"A Wahab",
"L Fechtenbaum",
"A Dormeuil",
"H Hosseini",
"K Youssov",
"G Fénelon",
"B Bapst",
"P Brugières",
"T Tuilier",
"E Kalsoum",
"M... | Revue neurologique | 0035-3787 | 2021 | 10.1016/j.neurol.2021.01.004 | [
"Amyotrophic Lateral Sclerosis",
"Diaphragmatic ultrasonography",
"Phrenic nerve conduction",
"Pulmonary function tests"
] |
12,829,320 | Hypoxic induction of caspase-11/caspase-1/interleukin-1beta in brain microglia. | Caspase-11 is an inducible protease that plays an important role in both inflammation and apoptosis. Inflammatory stimuli induce and activate caspase-11, which is required for the activation of caspase-1 or interleukin-1beta (IL-1beta) converting enzyme (ICE). Caspase-1 in turn mediates the maturation of proinflammator... | [
"Nam-Gon Kim",
"Heasuk Lee",
"Eunyung Son",
"Oh-Young Kwon",
"Jae-Yong Park",
"Jae-Hoon Park",
"Gyeong Jae Cho",
"Wan Sung Choi",
"Kyoungho Suk"
] | Brain research. Molecular brain research | 0169-328X | 2003 | 10.1016/s0169-328x(03)00135-9 | [] |
35,601,382 | Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome mimicking herpes simplex encephalitis: A case report. | Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome presents with the features of herpes simplex encephalitis (HSE), which is rare and has been described in only a few case reports. Our case describes a 17-year-old female with no significant previous medical history presen... | [
"Wen-Gao Zeng",
"Wan-Min Liao",
"Jue Hu",
"Su-Fen Chen",
"Zhen Wang"
] | Radiology case reports | 1930-0433 | 2022 | 10.1016/j.radcr.2022.04.019 | [
"ADC, apparent diffusion coefficient",
"Basal ganglia calcification",
"CJD, Creutzfeldt-Jakob disease",
"CSF, cerebrospinal fluid",
"CT, computed tomography",
"Case report",
"CoQ10, coenzyme 10",
"DNA, deoxyribonucleic acid",
"DWI, diffusion weighted imaging",
"FLAIR, fluid attenuated inversion re... |
29,901,583 | Paraneoplastic limbic encephalitis associated with mixed olfactory neuroblastoma and craniopharyngioma: A case report and literature review. | Paraneoplastic limbic encephalitis (PLE) is a rare disorder of the nervous system associated with malignant disease. It has a subacute onset with the following symptoms: cognitive dysfunction, seizures, irritability, hallucinations, and short-term memory loss. Herein, we report the case of a 35-year-old man with PLE, a... | [
"Hiroshi Nagafuji",
"Hidenori Yokoi",
"Masachika Fujiwara",
"Dai Sato",
"Koichiro Saito"
] | Medicine | 1536-5964 | 2018 | 10.1097/MD.0000000000010932 | [] |
35,455,327 | Influenza and Other Prophylactic Vaccination Coverage in Polish Adult Patients Undergoing Allergen Immunotherapy-A Survey Study among Patients and Physicians. | Vaccines against infectious diseases may raise safety concerns in patients undergoing allergen immunotherapy (AIT). The objective of our study was to investigate influenza vaccine and other selected prophylactic vaccines coverage in patients treated with AIT and the attitude of physicians towards vaccinations in this g... | [
"Ewa Czerwińska",
"Marita Nittner-Marszalska",
"Janusz Zaryczański",
"Grzegorz Gąszczyk",
"Agnieszka Mastalerz-Migas",
"Leszek Szenborn"
] | Vaccines | 2076-393X | 2022 | 10.3390/vaccines10040576 | [
"allergen immunotherapy",
"influenza vaccine",
"prophylactic vaccines",
"vaccine coverage"
] |
19,846,119 | Clinical manifestations, diagnostic criteria and therapy of Hashimoto's encephalopathy: report of two cases. | Hashimoto's encephalopathy (HE) is a rare, still not well understood, autoimmune disease with neurological and psychiatric manifestations. and elevated titers of antithyroid antibodies in serum and cerebrospinal fluid (CSF) as a hallmark of the disease. Patients are mostly women. Current diagnostic criteria include cor... | [
"Milija Mijajlovic",
"Mihailo Mirkovic",
"Jelena Dackovic",
"Jasna Zidverc-Trajkovic",
"Nadezda Sternic"
] | Journal of the neurological sciences | 1878-5883 | 2010 | 10.1016/j.jns.2009.09.030 | [] |
28,457,675 | Four-segmented Rift Valley fever virus-based vaccines can be applied safely in ewes during pregnancy. | Rift Valley fever virus (RVFV) causes severe and recurrent outbreaks on the African continent and the Arabian Peninsula and continues to expand its habitat. This mosquito-borne virus, belonging to the genus Phlebovirus of the family Bunyaviridae contains a tri-segmented negative-strand RNA genome. Previously, we develo... | [
"Paul J Wichgers Schreur",
"Lucien van Keulen",
"Jet Kant",
"Jeroen Kortekaas"
] | Vaccine | 1873-2518 | 2017 | 10.1016/j.vaccine.2017.04.024 | [
"Ewes",
"Four-segmented",
"Gestation",
"Intranasal",
"RVFV-4s",
"Rift Valley fever virus",
"Safety",
"Teratogenic"
] |
32,141,617 | Phase 1 study of epacadostat in combination with atezolizumab for patients with previously treated advanced nonsmall cell lung cancer. | Epacadostat is a potent and highly selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1). Here we report results from the open-label, dose-escalation, Phase 1b ECHO-110 study evaluating epacadostat plus atezolizumab in patients with previously treated Stage IIIB/IV nonsmall cell lung cancer (NSCLC). Eligible pati... | [
"Matthew D Hellmann",
"Scott Gettinger",
"Laura Q M Chow",
"Michael Gordon",
"Mark M Awad",
"Edward Cha",
"Xiaohua Gong",
"Gongfu Zhou",
"Chris Walker",
"Lance Leopold",
"Rebecca S Heist"
] | International journal of cancer | 1097-0215 | 2020 | 10.1002/ijc.32951 | [
"atezolizumab",
"combination",
"epacadostat",
"nonsmall cell lung cancer"
] |
15,070,430 | A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS. | The neurological complications of HIV infection remain poorly understood. Clinically, in vivo 1H magnetic resonance spectroscopy (MRS) demonstrates brain injury caused by HIV infection even when the MRI is normal. Our goal was to undertsand the dynamics of cerebral injury by performing a longitudinal in vivo 1H MRS stu... | [
"Robert A Fuller",
"Susan V Westmoreland",
"Eva Ratai",
"Jane B Greco",
"John P Kim",
"Margaret R Lentz",
"Julian He",
"Prabhat K Sehgal",
"Eliezer Masliah",
"Elkan Halpern",
"Andrew A Lackner",
"R Gilberto González"
] | BMC neuroscience | 1471-2202 | 2004 | 10.1186/1471-2202-5-10 | [] |
22,341,308 | A humanised murine monoclonal antibody protects mice from Venezuelan equine encephalitis virus, Everglades virus and Mucambo virus when administered up to 48 h after airborne challenge. | Currently there are no licensed antiviral treatments for the Alphaviruses Venezuelan equine encephalitis virus (VEEV), Everglades virus and Mucambo virus. We previously developed a humanised version of the mouse monoclonal antibody 1A3B-7 (Hu1A3B-7) which exhibited a wide range of reactivity in vitro and was able to pr... | [
"Lyn M O'Brien",
"Sarah A Goodchild",
"Robert J Phillpotts",
"Stuart D Perkins"
] | Virology | 1096-0341 | 2012 | 10.1016/j.virol.2012.01.038 | [] |
32,920,307 | Autoimmune Epilepsy in Children: Unraveling the Mystery. | Although many neurologists are familiar with the clinical presentations of anti-N-methyl-d-aspartate receptor or limbic encephalitides, there remains much mystery surrounding autoimmune etiologies of subacute and chronic epilepsies. In addition, the subtleties and differences in presentation in the pediatric population... | [
"Linda D Leary"
] | Pediatric neurology | 1873-5150 | 2020 | 10.1016/j.pediatrneurol.2020.03.016 | [
"Cell surface antibodies",
"Encephalitis",
"Immunotherapy",
"Refractory epilepsy",
"Seizures"
] |
33,555,596 | Rodent Models of Congenital Cytomegalovirus Infection. | Human cytomegalovirus (HCMV) is a leading viral cause of congenital infections in the central nervous system (CNS) and may result in severe long-term sequelae. High rates of sequelae following congenital HCMV infection and insufficient antiviral therapy in the perinatal period makes the development of an HCMV-specific ... | [
"Berislav Lisnić",
"Jelena Tomac",
"Djurdjica Cekinović",
"Stipan Jonjić",
"Vanda Juranić Lisnić"
] | Methods in molecular biology (Clifton, N.J.) | 1940-6029 | 2021 | 10.1007/978-1-0716-1111-1_18 | [
"Brain",
"Congenital infections",
"Cytomegalovirus"
] |
19,525,015 | Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury. | Local CNS inflammation takes place in many neurological disorders and is important for autoimmune neuroinflammation. Microglial activation is strain-dependent in rats and differential MHC class II expression is influenced by variations in the Mhc2ta gene. Despite sharing Mhc2ta and MHC class II alleles, BN and LEW.1N r... | [
"Margarita Diez",
"Nada Abdelmagid",
"Karin Harnesk",
"Mikael Ström",
"Olle Lidman",
"Maria Swanberg",
"Rickard Lindblom",
"Faiez Al-Nimer",
"Maja Jagodic",
"Tomas Olsson",
"Fredrik Piehl"
] | Journal of neuroimmunology | 1872-8421 | 2009 | 10.1016/j.jneuroim.2009.05.004 | [] |
15,644,073 | Temporal lobe epilepsy: analysis of failures and the role of reoperation. | To analyze failures and reoperations in temporal lobe epilepsy (TLE), and compare these patients with those seizure-free, and to determine any significant differences between the groups. | [
"V Salanova",
"O Markand",
"R Worth"
] | Acta neurologica Scandinavica | 0001-6314 | 2005 | 10.1111/j.1600-0404.2005.00371.x | [] |
34,906,391 | Beneficial and detrimental functions of microglia during viral encephalitis. | Microglia are resident immune cells of the central nervous system (CNS) with multiple functions in health and disease. Their response during encephalitis depends on whether inflammation is triggered in a sterile or infectious manner, and in the latter case on the type of the infecting pathogen. Even though recent techn... | [
"Inken Waltl",
"Ulrich Kalinke"
] | Trends in neurosciences | 1878-108X | 2022 | 10.1016/j.tins.2021.11.004 | [
"CNS infection",
"antiviral defence",
"brain immune response",
"cellular crosstalk",
"microglia"
] |
11,172,102 | Innate resistance to flavivirus infection in mice controlled by Flv is nitric oxide-independent. | Innate resistance to flaviviruses in mice is active in the brain where it restricts virus replication. This resistance is controlled by a single genetic locus, FLV, located on mouse chromosome 5 near the locus encoding the neuronal form of nitric oxide synthase (Nos1). Since nitric oxide (NO) has been implicated in ant... | [
"Ondine J Silvia",
"Geoffrey R Shellam",
"Nadezda Urosevic"
] | The Journal of general virology | 0022-1317 | 2001 | 10.1099/0022-1317-82-3-603 | [] |
11,564,771 | Plasmid DNA encoding CCR7 ligands compensate for dysfunctional CD8+ T cell responses by effects on dendritic cells. | Lymphotoxin alpha-deficient (LTalpha-/-) mice, which lack lymph nodes and possess a disorganized spleen, develop dysfunctional CD8+ T cells upon HSV infection and readily succumb to herpes encephalitis. Such mice do develop apparently normal peptide-specific CD8+ T cell responses, as measured by MHC class I tetramer st... | [
"S K Eo",
"U Kumaraguru",
"B T Rouse"
] | Journal of immunology (Baltimore, Md. : 1950) | 0022-1767 | 2001 | 10.4049/jimmunol.167.7.3592 | [] |
36,424,467 | CSF tau microtubule-binding region identifies pathological changes in primary tauopathies. | Despite recent advances in fluid biomarker research in Alzheimer's disease (AD), there are no fluid biomarkers or imaging tracers with utility for diagnosis and/or theragnosis available for other tauopathies. Using immunoprecipitation and mass spectrometry, we show that 4 repeat (4R) isoform-specific tau species from m... | [
"Kanta Horie",
"Nicolas R Barthélemy",
"Salvatore Spina",
"Lawren VandeVrede",
"Yingxin He",
"Ross W Paterson",
"Brenton A Wright",
"Gregory S Day",
"Albert A Davis",
"Celeste M Karch",
"William W Seeley",
"Richard J Perrin",
"Rama K Koppisetti",
"Faris Shaikh",
"Argentina Lario Lago",
... | Nature medicine | 1546-170X | 2022 | 10.1038/s41591-022-02075-9 | [] |
12,951,201 | Time-course of the expression of inflammatory cytokines and matrix metalloproteinases in the striatum and mesencephalon of mice injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a dopaminergic neurotoxin. | Injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice results in a retrograde nigrostriatal dopaminergic pathway denervation and subsequent tissue reorganization. Since the role of inflammatory mediators after MPTP remains unclear, proinflammatory cytokine and matrix metalloproteinase (MMP) expressio... | [
"Guillaume Hébert",
"Josette Arsaut",
"Robert Dantzer",
"Jacques Demotes-Mainard"
] | Neuroscience letters | 0304-3940 | 2003 | 10.1016/s0304-3940(03)00832-2 | [] |
36,331,771 | Detection and Analysis of West Nile Virus Structural Protein Genes in Animal or Bird Samples. | West Nile virus (WNV) is an important zoonotic pathogen, which is detected mainly by identification of its RNA using PCR. Genetic differentiation between WNV lineages is usually performed by complete genome sequencing, which is not available in many research and diagnostic laboratories. In this chapter, we describe a p... | [
"Gili Schvartz",
"Sharon Karniely",
"Roberto Azar",
"Areej Kabat",
"Amir Steinman",
"Oran Erster"
] | Methods in molecular biology (Clifton, N.J.) | 1940-6029 | 2023 | 10.1007/978-1-0716-2760-0_13 | [
"Nested PCR",
"Quantitative PCR",
"Sequencing",
"West Nile virus"
] |
21,530,328 | The calcium sensors STIM1 and STIM2 control B cell regulatory function through interleukin-10 production. | A chief Ca(2+) entry pathway in immune cells is store-operated Ca(2+) (SOC) influx, which is triggered by depletion of Ca(2+) from the endoplasmic reticulum (ER). However, its physiological role in B cells remains elusive. Here, we show that ER calcium sensors STIM1- and STIM2-induced SOC influx is critical for B cell ... | [
"Masanori Matsumoto",
"Yoko Fujii",
"Akemi Baba",
"Masaki Hikida",
"Tomohiro Kurosaki",
"Yoshihiro Baba"
] | Immunity | 1097-4180 | 2011 | 10.1016/j.immuni.2011.03.016 | [] |
35,704,066 | [The anti-IgLON5 syndrome in clinical neurology-Report of two cases]. | No abstract available | [
"Johanna Niederschweiberer",
"Nicolas U Schumacher",
"Daniela Kumpfmüller",
"Charlotte Lingg",
"Simone Graf",
"Benno Ikenberg",
"Mark Mühlau",
"Paul Lingor",
"Bernhard Hemmer",
"Benjamin Knier"
] | Der Nervenarzt | 1433-0407 | 2022 | 10.1007/s00115-022-01344-9 | [] |
12,771,574 | Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. | Nuclear factor-kappaB (NFkappaB) is a transcription factor that is activated after cerebral ischemia. NFkappaB activation leads to the expression of many inflammatory genes involved in the pathogenesis of stroke. The authors previously showed that mild hypothermia is protective even when cooling begins 2 h after stroke... | [
"Hyung Soo Han",
"Murat Karabiyikoglu",
"Stephen Kelly",
"Raymond A Sobel",
"Midori A Yenari"
] | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism | 0271-678X | 2003 | 10.1097/01.WCB.0000059566.39780.8D | [] |
34,735,692 | Multiple demyelinating sensory and motor mononeuropathy associated with COVID-19: a case report. | The involvement of the nervous system may occur in 36.4% of patients with COVID-19. Cases have been described of cerebrovascular diseases, encephalitis, encephalopathies, and changes in smell and taste. Two months after being discharged from hospital with COVID-19, a 63-year-old male patient presented with a predominan... | [
"Felipe Araújo Andrade de Oliveira",
"José Ricardo Bandeira de Oliveira Filho",
"Pedro Augusto Sampaio Rocha-Filho"
] | Journal of neurovirology | 1538-2443 | 2021 | 10.1007/s13365-021-01024-5 | [
"COVID-19",
"Multiple sensory and motor demyelinating mononeuropathy",
"Neuromuscular disorders",
"Peripheral nervous system",
"SARS-CoV-2"
] |
22,288,343 | [Infectious encephalitis]. | Infectious encephalitis is a severe disease of the central nervous system with high case fatality ratio and long-term sequels. Although a high proportion remains unexplained, the most frequently identified cause in all countries was always herpes simplex virus type 1. The generalisation of acyclovir dramatically improv... | [
"Jean-Paul Stahl",
"Pierre Tattevin"
] | La Revue du praticien | 0035-2640 | 2011 | No DOI available | [] |
29,873,694 | The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells. | Multiple sclerosis is an inflammatory demyelinating disease in which active demyelination and neurodegeneration are associated with lymphocyte infiltrates in the brain. However, so far little is known regarding the phenotype and function of these infiltrating lymphocyte populations. In this study, we performed an in-de... | [
"Joana Machado-Santos",
"Etsuji Saji",
"Anna R Tröscher",
"Manuela Paunovic",
"Roland Liblau",
"Galina Gabriely",
"Christian G Bien",
"Jan Bauer",
"Hans Lassmann"
] | Brain : a journal of neurology | 1460-2156 | 2018 | 10.1093/brain/awy151 | [] |
19,358,445 | In vitro propagation of rabies virus in mouse dorsal root ganglia cells. | Rabies virus (RV) is highly neurotropic and migrates to the neuronal soma by retrograde axonal transport from nerve terminals, after which it is taken by anterograde axonal transport to be finally released into the central nervous system (CNS) from which it disseminates, resulting in lethal encephalitis. Dorsal root ga... | [
"Yoko Hara",
"Yuji Sunden",
"Kenji Ochiai",
"Takashi Umemura"
] | The Japanese journal of veterinary research | 0047-1917 | 2009 | No DOI available | [] |
23,947,986 | Failure in developing high-level visual functions after occipitoparietal lesions at an early age: a case study. | Previous functional magnetic resonance imaging (fMRI) studies have identified several regions in the ventral visual pathway that are specialized for processing faces, words and general objects. However, little is known about the origin of the functional selectivity of these regions. Here, we reported a pediatric patien... | [
"Siyuan Hu",
"Hua Jin",
"Zhuoming Chen",
"Lei Mo",
"Jia Liu"
] | Cortex; a journal devoted to the study of the nervous system and behavior | 1973-8102 | 2013 | 10.1016/j.cortex.2013.07.009 | [
"Cortical lesion",
"Development",
"Early visual cortex",
"Object selectivity",
"Ventral visual pathway"
] |
35,259,208 | Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease. | Anti-IgLON5 disease is a newly defined clinical entity characterized by a progressive course with high disability and mortality rate. While precise pathogenetic mechanisms remain unclear, features characteristic of both autoimmune and neurodegenerative diseases were reported. Data on immunotherapy are limited, and its ... | [
"Thomas Grüter",
"Franziska E Möllers",
"Anja Tietz",
"Justina Dargvainiene",
"Nico Melzer",
"Anna Heidbreder",
"Christine Strippel",
"Andrea Kraft",
"Romana Höftberger",
"Florian Schöberl",
"Franziska S Thaler",
"Jonathan Wickel",
"Ha-Yeun Chung",
"Frank Seifert",
"Marlene Tschernatsch"... | Brain : a journal of neurology | 1460-2156 | 2023 | 10.1093/brain/awac090 | [
"HLA-DRB1*10:01",
"IgG subclass",
"anti-IgLON5 disease",
"immunotherapy",
"neurofilament light chain"
] |
20,205,646 | Mechanisms of action of non-steroidal anti-inflammatory drugs for the prevention of Alzheimer's disease. | Alzheimer's disease (AD) is accompanied by an activation of the innate immune system, and many epidemiological studies have shown reduced risk for dementia or AD associated with chronic consumption of non-steroidal anti-inflammatory drugs (NSAIDs). These observations led to animal model studies to test the hypothesis t... | [
"Greg M Cole",
"Sally A Frautschy"
] | CNS & neurological disorders drug targets | 1996-3181 | 2010 | 10.2174/187152710791011991 | [] |
21,434,803 | New Japanese encephalitis vaccines: alternatives to production in mouse brain. | Japanese encephalitis virus (JEV), a flavivirus maintained in a zoonotic cycle and transmitted by the mosquito Culex tritaeniorhynchus, causes epidemics of encephalitis throughout much of Asia. Resident populations, including short- or long-term visitors to enzootic regions, are at risk of infection and disease. For th... | [
"Scott B Halstead",
"Stephen J Thomas"
] | Expert review of vaccines | 1744-8395 | 2011 | 10.1586/erv.11.7 | [] |
31,707,133 | High risk of subacute sclerosing panencephalitis following measles outbreaks in Georgia. | To describe cases and estimate subacute sclerosing panencephalitis (SSPE) risk following large-sale measles outbreaks in Georgia. A rare, fatal late complication of measles, SSPE is often overlooked in assessments focused on the acute illness. Georgia had 8377 and 11,495 reported measles cases during the 2004-2005 and ... | [
"N Khetsuriani",
"K Sanadze",
"M Abuladze",
"N Tatishvili"
] | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 1469-0691 | 2020 | 10.1016/j.cmi.2019.10.035 | [
"Burden of measles",
"Georgia",
"Measles",
"Measles complications",
"Subacute sclerosing panencephalitis"
] |
15,001,748 | Genetics. Hybrid mosquitoes suspected in West Nile virus spread. | No abstract available | [
"Jennifer Couzin"
] | Science (New York, N.Y.) | 1095-9203 | 2004 | 10.1126/science.303.5663.1451a | [] |
11,751,998 | Association of prolonged survival in HLA-A2+ progressive multifocal leukoencephalopathy patients with a CTL response specific for a commonly recognized JC virus epitope. | The role of JC virus (JCV)-specific CTL was explored in the immunopathogenesis of progressive multifocal leukoencephalopathy (PML). We identified a 9-aa epitope of the JCV capsid protein VP1, the VP1(p100) peptide ILMWEAVTL, which is recognized by CTL of HLA-A2+ HIV+/PML survivors. We then constructed an HLA-A*0201/VP1... | [
"Igor J Koralnik",
"Renaud A Du Pasquier",
"Marcelo J Kuroda",
"Jörn E Schmitz",
"Xin Dang",
"Yue Zheng",
"Michelle Lifton",
"Norman L Letvin"
] | Journal of immunology (Baltimore, Md. : 1950) | 0022-1767 | 2002 | 10.4049/jimmunol.168.1.499 | [] |
12,242,424 | Infectious disease. Bird advocates fear that West Nile virus could silence the spring. | No abstract available | [
"David Malakoff"
] | Science (New York, N.Y.) | 1095-9203 | 2002 | 10.1126/science.297.5589.1989 | [] |
17,981,637 | Nucleic acid-based inhibition of flavivirus infections. | The genus Flavivirus in the family Flaviviridae consists of many arthropod-transmitted human pathogens, including dengue, yellow fever, Japanese encephalitis, West Nile, St. Louis encephalitis, Murray Valley encephalitis, and tick-borne encephalitis viruses. Treatment options against flaviviral disease are extremely li... | [
"David A Stein",
"Pei-Yong Shi"
] | Frontiers in bioscience : a journal and virtual library | 1093-9946 | 2008 | 10.2741/2769 | [] |
33,014,342 | High vaccination coverage and inadequate knowledge: Findings from a community-based cross-sectional study on Japanese Encephalitis in Yangon, Myanmar. | <b>Background:</b> Japanese encephalitis (JE) is a mosquito-borne disease with high case fatality and no specific treatment. Little is known about the community's (especially parents/guardians of children) awareness regarding JE and its vaccine in Yangon region, which bears the highest JE burden in Myanmar. <b>Methods:... | [
"Pyae Phyo Kyaw",
"Hemant Deepak Shewade",
"Nang Thu Thu Kyaw",
"Khaing Hnin Phyo",
"Htar Htar Lin",
"Aye Mon Mon Kyaw",
"Mg Mg Mya",
"Sein Thaung",
"Yan Naung Maung Maung"
] | F1000Research | 2046-1402 | 2020 | 10.12688/f1000research.21702.3 | [
"JE vaccine",
"SORT IT",
"caregiver’s knowledge",
"community-based survey",
"knowledge and perception"
] |
34,411,895 | Antiamoeboid activity of squamins C-F, cyclooctapeptides from Annona globifora. | Free-living amoebae of Acanthamoeba spp. are causative agents of human infections such as granulomatous amoebic encephalitis (GAE) and Acanthamoeba keratitis (AK). The exploration of innovative chemical entities from natural sources that induce intrinsic apoptotic pathway or a Programmed Cell Death (PCD) in Acanthamoeb... | [
"Rubén L Rodríguez-Expósito",
"Javier Sosa-Rueda",
"María Reyes-Batlle",
"Ines Sifaoui",
"Francisco Cen-Pacheco",
"Antonio Hernández Daranas",
"Ana R Díaz-Marrero",
"José E Piñero",
"José J Fernández",
"Jacob Lorenzo-Morales"
] | International journal for parasitology. Drugs and drug resistance | 2211-3207 | 2021 | 10.1016/j.ijpddr.2021.08.003 | [
"Acanthamoeba",
"Annona",
"Antiamoeboid",
"Cyclopeptide",
"Squamin"
] |
11,346,819 | [Acute disseminated encephalomyelitis in childhood. Report of 10 cases]. | Acute disseminated encephalomyelitis (ADEM) is a postinfectious encephalitis that is usually preceded by an infectious disease or vaccination. The clinical presentation has a wide spectrum and complementary exams are none specific, except magnetic resonance imaging (MRI) findings showing multifocal white-matter lesions... | [
"J Campistol Plana",
"F J Cambra",
"M Guitet Julià"
] | Revista de neurologia | 0210-0010 | No publication year available | No DOI available | [] |
30,451,627 | Pathology in Practice. | No abstract available | [
"Ryan M Schafbuch",
"Jesús A Hermida Casas",
"G Kenitra Hammac",
"Janice E Kritchevsky",
"Margaret A Miller"
] | Journal of the American Veterinary Medical Association | 1943-569X | 2018 | 10.2460/javma.253.11.1417 | [] |
36,128,810 | [Other Central Nervous System Infections(Including Fungal Infection, Tuberculosis, and Parasitic Infection)]. | This review describes cryptococcal meningoencephalitis, tuberculous meningitis, neurosyphilis, and toxoplasma encephalitis. Central nervous system infections are neurological emergencies associated with mortality or other outcomes. Therefore, early diagnosis and treatment are critical. Fungal or gondii infections are r... | [
"Ryuusuke Takaki",
"Yoshihisa Takiyama"
] | No shinkei geka. Neurological surgery | 0301-2603 | 2022 | 10.11477/mf.1436204654 | [] |
16,765,602 | Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice. | The present study assessed the influence of dietary lipids on accumulation of amyloid beta-peptide (Abeta) in the brain. Seven experimental diets with varying n-6/n-3-ratio, saturated and polyunsaturated fatty acid and cholesterol contents were fed to transgenic APPswe/PS1dE9 mice for 3-4 months beginning at a young ad... | [
"M Oksman",
"H Iivonen",
"E Hogyes",
"Z Amtul",
"B Penke",
"I Leenders",
"L Broersen",
"D Lütjohann",
"T Hartmann",
"H Tanila"
] | Neurobiology of disease | 0969-9961 | 2006 | 10.1016/j.nbd.2006.04.013 | [] |
26,789,900 | More on PML in Patients Treated with Dimethyl Fumarate. | No abstract available | [
"Kristian Reich",
"Hans-Peter Hartung",
"Mark Lebwohl"
] | The New England journal of medicine | 1533-4406 | 2016 | 10.1056/NEJMc1512228 | [] |
34,521,234 | A Case of Disseminated Cutaneous Herpes Simplex Virus-1 as the First Manifestation of Human Immunodeficiency Virus Infection. | Reported clinical manifestations of active herpes simplex virus type 1 (HSV-1) infection include typically painful vesicular cutaneous rash in a dermatomal distribution, temporal lobe encephalitis, and rarely, fulminant septic shock with multiorgan failure. In immunocompromised patients, the cutaneous rash can become d... | [
"Parker Brown",
"Sandra Elmasry",
"Abdulbaril Olagunju",
"Santiago Garcia",
"Mansi Sarihan"
] | Journal of investigative medicine high impact case reports | 2324-7096 | 2021 | 10.1177/23247096211045245 | [
"acyclovir",
"cutaneous",
"dermatology",
"disseminated",
"herpes simplex virus",
"human immunodeficiency virus"
] |
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