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34,270,107
Validation of serum apolipoprotein A1 in rabies virus-infected mice as a biomarker for the preclinical diagnosis of rabies.
Rabies is a type of acute fetal encephalitis caused by rabies virus (RABV). While it becomes incurable after symptom onset, it can be prevented by post-exposure prophylaxis (PEP) during the long incubation period. While preclinical diagnosis aids the appropriate PEP administration, it is mostly nonfeasible owing to the...
[ "Kentaro Yamada", "Koji Kuribayashi", "Naotaka Inomata", "Kazuko Noguchi", "Kazunori Kimitsuki", "Catalino S Demetria", "Nobuo Saito", "Satoshi Inoue", "Chun-Ho Park", "Ryo Kaimori", "Motoi Suzuki", "Mariko Saito-Obata", "Yasuhiko Kamiya", "Daria L Manalo", "Beatriz P Quiambao", "Akira...
Microbiology and immunology
1348-0421
2021
10.1111/1348-0421.12929
[ "ApoA1", "biomarker", "in vivo imaging", "proteomics", "rabies" ]
12,034,805
Spatial and temporal disease progression of adult-onset subacute sclerosing panencephalitis.
An adult-onset case of subacute sclerosing panencephalitis with occipitofrontal spread of the infection documented clinically and by MRI is reported. Autopsy revealed numerous intranuclear viral inclusions and widespread demyelination in both frontal lobes. In the occipital lobes where the disease started 5 years previ...
[ "C Mawrin", "H Lins", "B Koenig", "T Heinrichs", "S Murayama", "E Kirches", "C Boltze", "K Dietzmann" ]
Neurology
0028-3878
2002
10.1212/wnl.58.10.1568
[]
25,709,948
Balamuthia mandrillaris: Morphology, biology, and virulence.
Balamuthia mandrillaris is a protist pathogen that can cause encephalitis with a fatality rate of >95%. This is due to our incomplete understanding of the pathogenesis and pathophysiology of B. mandrillaris encephalitis. B. mandrillaris has two stages in its life cycle, an active trophozoite stage during which it divid...
[ "Ruqaiyyah Siddiqui", "Naveed Ahmed Khan" ]
Tropical parasitology
2229-5070
2015
10.4103/2229-5070.149888
[ "Balamuthia mandrillaris", "biology", "encephalitis", "morphology", "pathogenesis", "virulence" ]
18,393,089
A recombinant avian leukosis virus associated with fowl glioma in layer chickens in Japan.
Fowl glioma is characterized by multiple nodular growth of astrocytes, and fowl glioma-inducing virus belonging to avian leukosis virus has been isolated from Japanese bantam as a causal agent. Subcutaneous neoplasms of the head and neck have been reported in layer chickens since 2003 in Japan, and fowl glioma concurre...
[ "Hitoshi Hatai", "Kenji Ochiai", "Katsue Nagakura", "Syunsuke Imanishi", "Akihiro Ochi", "Rie Kozakura", "Masaaki Ono", "Masanobu Goryo", "Kazuhiko Ohashi", "Takashi Umemura" ]
Avian pathology : journal of the W.V.P.A
1465-3338
2008
10.1080/03079450801898815
[]
24,323,769
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
We previously reported that glioma cells induce the expression of membrane-type 1 metalloproteinase (MT1-MMP or MMP-14) in tumor-associated microglia/macrophages and promote tumor growth, whereas MMP-14 expression in microglia under physiological conditions is very low. Here, we show that the increase in MMP-14 express...
[ "Anika Langenfurth", "Jan Leo Rinnenthal", "Katyayni Vinnakota", "Vincent Prinz", "Anne-Sophie Carlo", "Christine Stadelmann", "Volker Siffrin", "Susann Peaschke", "Matthias Endres", "Frank Heppner", "Rainer Glass", "Susanne A Wolf", "Helmut Kettenmann" ]
Journal of neuroscience research
1097-4547
2014
10.1002/jnr.23288
[ "Alzheimer's disease", "MMP-14", "MT1-MMP", "amyotrophic lateral sclerosis", "macrophages", "metalloproteinase", "microglia", "multiple sclerosis", "neurodegeneration", "neuroinflammation", "stroke", "trauma" ]
26,768,126
Comparable immune responsiveness but increased reactogenicity after subcutaneous versus intramuscular administration of tick borne encephalitis (TBE) vaccine.
Evaluation of safety, immunogenicity and efficacy of vaccines during licensing studies is performed in relation to the selected vaccination route. For most adjuvanted vaccines, such as the TBE vaccine FSME-IMMUN, only intramuscular (i.m.) administration is licensed. Yet in certain situations, either because of medical ...
[ "Stefan Hopf", "Erika Garner-Spitzer", "Michael Hofer", "Michael Kundi", "Ursula Wiedermann" ]
Vaccine
1873-2518
2016
10.1016/j.vaccine.2015.12.057
[ "BMI", "Cellular", "Humeral", "Immune response", "Immunogenicity", "Intramuscular", "Local", "Safety", "Side effects", "Subcutaneous", "Systemic", "TBE", "Vaccination route", "Vaccine" ]
37,512,806
Tick-Borne Encephalitis Virus: A Comprehensive Review of Transmission, Pathogenesis, Epidemiology, Clinical Manifestations, Diagnosis, and Prevention.
Tick-borne encephalitis virus (TBEV), a member of the <i>Flaviviridae</i> family, can cause serious infection of the central nervous system in humans, resulting in potential neurological complications and fatal outcomes. TBEV is primarily transmitted to humans through infected tick bites, and the viral agent circulates...
[ "Emina Pustijanac", "Moira Buršić", "Jasminka Talapko", "Ivana Škrlec", "Tomislav Meštrović", "Dubravka Lišnjić" ]
Microorganisms
2076-2607
2023
10.3390/microorganisms11071634
[ "TBEV", "clinical manifestations", "diagnosis of TBEV", "epidemiology of TBEV", "tick-borne encephalitis virus", "transmission and circulation in nature" ]
25,282,450
[Two pediatric cases of anti-NMDA receptor antibody encephalitis].
Although less frequent than viral encephalitis, anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a frequent form of acute pediatric encephalitis. After a prodromal phase of flu-like symptoms, psychiatric symptoms predominate - agitation, anxiety, hallucinations - and can make correct diagnosis more difficult....
[ "M Ben Azoun", "S Tatencloux", "K Deiva", "P Blanc" ]
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
1769-664X
2014
10.1016/j.arcped.2014.08.020
[]
12,069,521
Construction and characterization of subgenomic replicons of New York strain of West Nile virus.
The lineage I strain of West Nile virus (WNV) frequently causes human epidemics, including the recent outbreak in North America (Lanciotti et al., 1999, Science 286:2333-2337). As an initial step in studying the replication and pathogenesis of WNV, we constructed several cDNA clones of a WNV replicon derived from an ep...
[ "Pei-Yong Shi", "Mark Tilgner", "Michael K Lo" ]
Virology
0042-6822
2002
10.1006/viro.2002.1453
[]
23,296,919
Neuroinflammation: beneficial and detrimental effects after traumatic brain injury.
Traumatic brain injury (TBI) is the major cause of death and severe disability in young adults and infants worldwide and many survivors also have mild to moderate neurological deficits which impair their lives. This review highlights the primary and secondary lesions constituting craniocerebral trauma and the main elem...
[ "J W Finnie" ]
Inflammopharmacology
1568-5608
2013
10.1007/s10787-012-0164-2
[]
37,254,846
Antiviral effect of Favipiravir against Chandipura virus in vitro and in vivo.
Chandipura virus (CHPV) is an emerging encephalitic virus with outbreak potential in a pediatric population. It causes acute encephalitis, with clinical symptoms leading to death within 48-72 h and an alarmingly high case fatality rate up to 55%-78%. Despite the high mortality rate in children, no vaccines or antiviral...
[ "Daya V Pavitrakar", "Vijay P Bondre" ]
Journal of medical virology
1096-9071
2023
10.1002/jmv.28840
[ "Chandipura Virus", "Favipiravir", "RdRp inhibitor", "acute viral encephalitis", "antivirals" ]
33,410,601
Flortaucipir (tau) PET in LGI1 antibody encephalitis.
The contributors to persistent cognitive impairment and hippocampal atrophy in leucine-rich glioma-inactivated 1 antibody encephalitis (LGI1) patients are unknown. We evaluated whether tau neuropathology measured with [<sup>18</sup> F]flortaucipir PET neuroimaging associated with persistent cognitive impairment and hip...
[ "Gregory S Day", "Brian A Gordon", "Austin McCullough", "Robert C Bucelli", "Richard J Perrin", "Tammie L S Benzinger", "Beau M Ances" ]
Annals of clinical and translational neurology
2328-9503
2021
10.1002/acn3.51297
[]
17,150,441
Epileptic seizures in the pediatric intensive care unit setting.
The clinical features of seizures occurring in the pediatric intensive care unit (PICU) setting are not well characterized. Adult ICU studies reveal an incidence of seizures ranging from 0.8% to 3.3%, with vascular, metabolic abnormalities, and drug withdrawal being the most common etiologies. The objective of this stu...
[ "Ignacio Valencia", "Germán Lozano", "Sanjeev V Kothare", "Joseph J Melvin", "Divya S Khurana", "H Huntley Hardison", "Sabrina S Yum", "Agustín Legido" ]
Epileptic disorders : international epilepsy journal with videotape
1294-9361
2006
No DOI available
[]
23,637,179
Glucocorticoid signaling in myeloid cells worsens acute CNS injury and inflammation.
Glucocorticoid stress hormones (GCs) are well known for being anti-inflammatory, but some reports suggest that GCs can also augment aspects of inflammation during acute brain injury. Because the GC receptor (GR) is ubiquitously expressed throughout the brain, it is difficult to know which cell types might mediate these...
[ "Shawn F Sorrells", "Javier R Caso", "Carolina D Munhoz", "Caroline K Hu", "Kevin V Tran", "Zurine D Miguel", "Bonnie Y Chien", "Robert M Sapolsky" ]
The Journal of neuroscience : the official journal of the Society for Neuroscience
1529-2401
2013
10.1523/JNEUROSCI.4705-12.2013
[]